Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29375450 | 0.96 | TSHR (0.61) | TSHRKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL16863053 | 0.96 | TSHR (0.61) | TSHRKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL25707 | 0.96 | TSHR (0.61) | TSHRKDM4EDUSP3MEN1KMT2A | |
| Methane SCHEMBL28897391 | 0.94 | TSHR (0.59) | TSHRKDM4EDUSP3MEN1KMT2A | |
| Ethylene SCHEMBL27572484 | 0.94 | TSHR (0.59) | TSHRKDM4EDUSP3MEN1KMT2A | |
| Glycerin SCHEMBL28100194 | 0.94 | TSHR (0.59) | TSHRKDM4EDUSP3MEN1KMT2A | |
| Propanol SCHEMBL27929363 | 0.93 | TSHR (0.53) | TSHRKDM4EDUSP3MEN1KMT2A | |
| Bicarbonate SCHEMBL28904630 | 0.92 | TSHR (0.57) | TSHRKDM4EDUSP3MEN1KMT2A | |
| Methacrylic Acid SCHEMBL25415594 | 0.91 | TSHR (0.55) | TSHRKDM4EDUSP3MEN1KMT2A | |
| Methacrylic Acid SCHEMBL5435140 | 0.91 | TSHR (0.55) | TSHRKDM4EDUSP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144865-B1 | METHOD FOR PRODUCING DIOLS | COGNIS IP MAN GMBH (DE) | 2016-07-13 | — | — | EP | disclosed |
| US-7645846-B2 | Useful as monomer for the preparation of hemocompatible coating, medical device, water soluble polymer material, paint, water borne coating, or an ocular device (contact lenses) | COOPERVISION INTERNATIONAL HOLDING COMPANY LP (BB) | 2010-01-12 | — | — | US | disclosed |
| US-7342054-B2 | Method for producing polymerisable polyhydroxy compounds | ROEHM GMBH & CO. KG (DE) | 2008-03-11 | — | — | US | disclosed |
| US-20060258830-A1 | Method for producing polymerisable polyhydroxy compounds | ROEHM GBMH & CO. KG (DE) | 2006-11-16 | — | — | US | disclosed |
| EP-1171411-B1 | PROCESS FOR THE PREPARATION OF A DIOL | COOPERVISION INT HOLDING CO LP (BB) | 2005-01-12 | — | — | EP | disclosed |
| EP-1171410-B1 | PROCESS FOR THE PREPARATION OF A DIOL | COOPERVISION INT HOLDING CO LP (BB) | 2004-12-08 | — | — | EP | disclosed |
| US-6610895-B2 | Useful as monomer for the preparation of hemocompatible coating, medical device, water soluble polymer material, paint, water borne coating, or ocular device (contact lenses) | HYDRON LIMITED (GB) | 2003-08-26 | — | — | US | disclosed |
| US-20020042546-A1 | Process for the preparation of a diol | COOPERVISION INTERNATIONAL LIMITED (GB) | 2002-04-11 | — | — | US | disclosed |
| US-20020042549-A1 | Process for the preparation of a diol | COOPERVISION INTERNATIONAL LIMITED (GB) | 2002-04-11 | — | — | US | disclosed |
| EP-1171410-A1 | PROCESS FOR THE PREPARATION OF A DIOL | Hydron Limited (GB) | 2002-01-16 | — | — | EP | disclosed |
| EP-1171411-A1 | PROCESS FOR THE PREPARATION OF A DIOL | Hydron Limited (GB) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000063150-A1 | PROCESS FOR THE PREPARATION OF A DIOL | HYDRON LIMITED (GB) | 2000-10-26 | — | — | WO | disclosed |
| WO-2000063149-A1 | PROCESS FOR THE PREPARATION OF A DIOL | HYDRON LIMITED (GB) | 2000-10-26 | — | — | WO | disclosed |
| WO-1998007055-A1 | PROCESS FOR PREPARING AN OCULAR DEVICE | HYDRON LIMITED (GB) | 1998-02-19 | — | — | WO | disclosed |
| EP-0298611-B1 | POLYURETHANES AND POLYURETHANE/POLYUREAS CROSSLINKED USING 2-GLYCERYL ACRYLATE OR 2-GLYCERYL METHACRYLATE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-08-04 | — | — | EP | disclosed |
| EP-0298611-A2 | Polyurethanes and polyurethane/polyureas crosslinked using 2-glyceryl acrylate or 2-glyceryl methacrylate | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-01-11 | — | — | EP | disclosed |
| US-4786657-A | BINDERS, DRESSINGS, MEMBRANES, PROTECTIVE COATINGS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-11-22 | — | — | US | disclosed |
| US-4338419-A | REDUCING IRRITATION FROW WEARING CONTACT LENSES | SYNTEX (U.S.A.) INC. (US) | 1982-07-06 | — | — | US | disclosed |
| US-4056496-A | ACRYLIC | CORNEAL SCIENCES, INC. (US) | 1977-11-01 | — | — | US | disclosed |
| US-3957362-A | Hydrogels and articles made therefrom | CORNEAL SCIENCES, INC. (US) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020042546-A1 | Process for the preparation of a diol | SI, SORD, ADH1C | TSHR 4421/4885KDM4E 3767/4885DUSP3 4469/4885 |
| US-20020042549-A1 | Process for the preparation of a diol | INHA, F12, F13A1 | TSHR 3801/4885KDM4E 3770/4885DUSP3 3858/4885 |
| US-20060258830-A1 | Method for producing polymerisable polyhydroxy compounds | GRHPR, GK, GMDS | TSHR 4781/4885KDM4E 1196/4885DUSP3 3334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.