SCHEMBL1398249

SCHEMBL1398249

C=C(C)C(=O)OCC(O)CO.CCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
KDM4E B2RXH2 1/20 0.38
DUSP3 P51452 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
LMNA P02545 1/20 0.38
DGKA P23743 1/20 0.34
THRB P10828 1/20 0.33
FAAH O00519 2/20 0.33
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5837613 0.96 TSHR (0.39) TSHRKDM4EDUSP3MEN1KMT2A
SCHEMBL5838352 0.89 TSHR (0.41) TSHRKDM4EDUSP3MEN1KMT2A
SCHEMBL1398234 0.89 TSHR (0.41) TSHRKDM4EDUSP3MEN1KMT2A
SCHEMBL2189982 0.86 TSHR (0.41) TSHRTHRBALDH1A1
SCHEMBL5838952 0.86 TSHR (0.46) TSHRKDM4EDUSP3MEN1KMT2A
SCHEMBL5837966 0.81 TSHR (0.41) TSHRKDM4EDUSP3MEN1KMT2A
Propanol SCHEMBL27929363 0.81 TSHR (0.53) TSHRKDM4EDUSP3MEN1KMT2A
Propane SCHEMBL3677972 0.81 TSHR (0.57) TSHRKDM4EDUSP3MEN1KMT2A
SCHEMBL25707 0.81 TSHR (0.61) TSHRKDM4EDUSP3MEN1KMT2A
SCHEMBL16863053 0.81 TSHR (0.61) TSHRKDM4EDUSP3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3220741-B1 COMPOSITION AND KITS FOR INHIBITION OF PATHOGENIC MICROBIAL INFECTION AND METHODS OF USING THE SAME ROCHAL IND LLC (US) 2021-02-24 EP claimed
EP-3220741-A1 COMPOSITION AND KITS FOR INHIBITION OF PATHOGENIC MICROBIAL INFECTION AND METHODS OF USING THE SAME Rochal Industries, LLC (US) 2017-09-27 EP claimed
EP-2764065-B1 SACRIFICIAL ADHESIVE COATINGS ROCHAL IND LLC (US) 2017-03-22 EP claimed
WO-2016054021-A1 COMPOSITION AND KITS FOR INHIBITION OF PATHOGENIC MICROBIAL INFECTION AND METHODS OF USING THE SAME ROCHAL INDUSTRIES, LLC (US) 2016-04-07 WO claimed
EP-2764065-A1 SACRIFICIAL ADHESIVE COATINGS Rochal Industries, LLP (US) 2014-08-13 EP claimed
WO-2013052276-A1 SACRIFICIAL ADHESIVE COATINGS ROCHAL INDUSTRIES, LLP (US) 2013-04-11 WO claimed
US-8263720-B1 Sacrificial adhesive coatings ROCHAL INDUSTRIES, LLP (US) 2012-09-11 US claimed
US-11839626-B2 Composition and kits for inhibition of pathogenic microbial infection and methods of using the same ROCHAL TECHNOLOGIES LLC (US) 2023-12-12 US disclosed
EP-3220741-B1 COMPOSITION AND KITS FOR INHIBITION OF PATHOGENIC MICROBIAL INFECTION AND METHODS OF USING THE SAME ROCHAL IND LLC (US) 2021-02-24 EP disclosed
EP-3052140-B1 NON-SELF-ADHERENT COATING MATERIALS ROCHAL IND LLC (US) 2019-05-01 EP disclosed
US-20170360825-A1 Composition and Kits for Inhibition of Pathogenic Microbial Infection and Methods of Using the Same ROCHAL INDUSTRIES, LLC (US) 2017-12-21 US disclosed
EP-3220741-A1 COMPOSITION AND KITS FOR INHIBITION OF PATHOGENIC MICROBIAL INFECTION AND METHODS OF USING THE SAME Rochal Industries, LLC (US) 2017-09-27 EP disclosed
EP-2764065-B1 SACRIFICIAL ADHESIVE COATINGS ROCHAL IND LLC (US) 2017-03-22 EP disclosed
US-20070129474-A1 Solution of an amphiphilic copolymer of a nitrogen-containing monomer, such as N-isopropylacrylamide, and a siloxy monomer, preferably 3-(methacryloyloxy)propyltris(trimethylsiloxy)silane in non-stinging, volatile, siloxane, alkane, fluorocarbon, lor iquid or supercritical carbon dioxide; medical devices ROCHAL INDUSTRIES, LLP. (US) 2007-06-07 US disclosed
US-7037954-B2 Ocular lens material MENICON CO., LTD. (JP) 2006-05-02 US disclosed
EP-1197782-B1 MATERIAL FOR OCULAR LENS MENICON CO LTD (JP) 2004-06-02 EP disclosed
US-20040039077-A1 Ocular lens material MENICON CO., LTD. 2004-02-26 US disclosed
US-6638991-B2 Lens material comprising a copolymer derived from a polysiloxane endcapped with acrylated urethane groups, a silicon-containing alkyl methacrylate, a hydrophilic monomer, and a crosslinking monomer; oxygen permeability, strength MENICON CO., LTD. (JP) 2003-10-28 US disclosed
US-20020198280-A1 Material for ocular lens MENICON CO., LTD. (JP) 2002-12-26 US disclosed
EP-1197782-A1 MATERIAL FOR OCULAR LENS MENICON CO., LTD. (JP) 2002-04-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170360825-A1 Composition and Kits for Inhibition of Pathogenic Microbial Infection and Methods of Using the Same CUTA, MMP8, MMP1 TSHR 3520/4885KDM4E 4848/4885DUSP3 1252/4885
US-11839626-B2 Composition and kits for inhibition of pathogenic microbial infection and methods of using the same CUTA, MMP8, MMP1 TSHR 3520/4885KDM4E 4848/4885DUSP3 1252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.