Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9456154 | 0.90 | CA12 (0.46) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL9456256 | 0.87 | CA12 (0.44) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL15821787 | 0.85 | CA12 (0.39) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL9456515 | 0.84 | CA12 (0.54) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL17226465 | 0.80 | CA12 (0.48) | CA12CA9CA2TSHRALDH1A1 | |
| SCHEMBL17226472 | 0.80 | CA12 (0.48) | CA12CA9CA2TSHRALDH1A1 | |
| SCHEMBL10445563 | 0.78 | CA12 (0.50) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL41505 | 0.77 | CA12 (0.55) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL52110 | 0.77 | LMNA (0.43) | CA12CA9CA2ALDH1A1HPGD | |
| SCHEMBL9456333 | 0.75 | CA12 (0.57) | CA12CA9CA2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2168957-B1 | Alkyl-substituted tetrahydropyranes as aromatic materials | SYMRISE AG (DE) | 2012-02-15 | — | — | EP | claimed |
| US-5232947-A | Administering to ameliorate damage from anoxia | MEIJI SEIKA KAISHA, LTD. (JP) | 1993-08-03 | — | — | US | claimed |
| US-20230340011-A1 | STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS | Asteroid Therapeutics | 2023-10-26 | — | — | US | disclosed |
| US-20230340011-A1 | STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS | Asteroid Therapeutics | 2023-10-26 | — | — | US | disclosed |
| CN-108473484-A | Compounds useful as TRPM8 modulators | 赛诺米克斯公司 | 2018-08-31 | — | — | CN | disclosed |
| EP-0350260-B1 | New oxamic acid compounds and pharmaceutical composition for use in improvement of damaged cerebral functions of brain | MEIJI SEIKA KAISHA (JP) | 1993-10-20 | — | — | EP | disclosed |
| US-5232947-A | Administering to ameliorate damage from anoxia | MEIJI SEIKA KAISHA, LTD. (JP) | 1993-08-03 | — | — | US | disclosed |
| EP-0350260-A2 | New oxamic acid compounds and pharmaceutical composition for use in improvement of damaged cerebral functions of brain | MEIJI SEIKA KAISHA LTD. (JP) | 1990-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230340011-A1 | STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS | SREBF1, SREBF2, NR1H3 | CA12 4344/4885CA9 3878/4885CA2 4355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.