Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.50 |
| ▸ | CA9 | Q16790 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL154162 | 0.79 | CA12 (0.46) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL583897 | 0.78 | CA12 (0.50) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL9076012 | 0.77 | LMNA (0.43) | CA12CA9CA2TSHRALDH1A1 | |
| SCHEMBL483128 | 0.77 | CA12 (0.55) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL13055370 | 0.74 | CA12 (0.52) | CA12CA9CA2TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL3020939 | 0.74 | CA12 (0.52) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL13055369 | 0.74 | CA12 (0.52) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL13055372 | 0.74 | CA12 (0.52) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL3468211 | 0.73 | CA12 (0.57) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL498285 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379979-A1 | Pyrazolopyridine compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-01 | — | — | EP | disclosed |