Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5839474 | 0.91 | SLC6A2 (0.36) | SLC6A2SLC6A4NR1H4LTB4R2CHRM1 | |
| SCHEMBL5838284 | 0.89 | SLC6A2 (0.37) | SLC6A2SLC6A4PTPRBPTPN11ATM | |
| SCHEMBL5718068 | 0.88 | ATM (0.40) | SLC6A2SLC6A4ATMLMNALTB4R2 | |
| SCHEMBL5839575 | 0.81 | KDM1A (0.34) | SLC6A2SLC6A4NR1H4LMNASTAT3 | |
| SCHEMBL5846941 | 0.80 | GAA (0.40) | LTB4R2CHRM2CHRM1CHRM3CHRM5 | |
| SCHEMBL5718166 | 0.80 | GAA (0.40) | LTB4R2CHRM2CHRM1CHRM3CHRM5 | |
| SCHEMBL7068481 | 0.80 | ATM (0.36) | SLC6A2SLC6A4PTPRBPTPN11ATM | |
| Bicarbonate SCHEMBL5718071 | 0.79 | STAT3 (0.46) | ATMLMNASTAT3CNR1CNR2 | |
| SCHEMBL5837873 | 0.78 | KCNQ3 (0.44) | SLC6A2SLC6A4ATMLTB4R2 | |
| SCHEMBL5838740 | 0.77 | PTPRB (0.42) | SLC6A2SLC6A4PTPRBPTPN11NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074780-B2 | Substituted phenylcyclohexanecarboxamides and their use | BAYER AKTIENGESELLSCHAFT (DE) | 2006-07-11 | — | — | US | disclosed |
| US-20040122004-A1 | Substituted phenylcyclohexanecarboxamides and their use | BAYER AKTIENGESELLSCHAFT (DE) | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122004-A1 | Substituted phenylcyclohexanecarboxamides and their use | TNNI3, PAH, P4HA1 | SLC6A2 1862/4885SLC6A4 2786/4885PTPRB 3782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.