Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | PTPRB | P23467 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067646 | 0.93 | SMN1; SMN2 (0.34) | SLC6A2CHRM2CHRM1CHRM3STAT3 | |
| SCHEMBL5838284 | 0.92 | SLC6A2 (0.37) | ATMSLC6A2SLC6A4PTPRBPTPN11 | |
| SCHEMBL5718068 | 0.85 | ATM (0.40) | ATMSLC6A2SLC6A4ALDH1A1CNR2 | |
| SCHEMBL5839575 | 0.84 | KDM1A (0.34) | SLC6A2SLC6A4ALDH1A1STAT3CNR2 | |
| SCHEMBL5838287 | 0.82 | ATM (0.33) | ATMPTPRBPTPN11ALDH1A1CHRM2 | |
| SCHEMBL5839005 | 0.80 | SLC6A2 (0.39) | ATMSLC6A2SLC6A4PTPRBPTPN11 | |
| SCHEMBL5846941 | 0.78 | GAA (0.40) | CHRM2CHRM1CHRM3STAT3CNR2 | |
| SCHEMBL5718166 | 0.78 | GAA (0.40) | CHRM2CHRM1CHRM3STAT3CNR2 | |
| SCHEMBL5839578 | 0.75 | TRPA1 (0.31) | CHRM1CHRM3STAT3CNR2CNR1 | |
| SCHEMBL5839474 | 0.72 | SLC6A2 (0.36) | SLC6A2SLC6A4CHRM1CHRM3STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6649616-B2 | For therapy and prophylaxis of cardiovascular disorders caused by ischaemia | BAYER AKTIENGESELLSCHAFT (DE) | 2003-11-18 | — | — | US | disclosed |
| US-20030008881-A1 | Substituted phenylcyclohexanecarboxamides and their use | BAYER AKTIENGESELLSCHAFT (DE) | 2003-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030008881-A1 | Substituted phenylcyclohexanecarboxamides and their use | TNNI3, PAH, P4HA1 | ATM 4611/4885SLC6A2 1862/4885SLC6A4 2786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.