Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 5/20 | 0.58 |
| ▸ | FABP5 | Q01469 | 5/20 | 0.58 |
| ▸ | FABP3 | P05413 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5669640 | 1.00 | FABP4 (0.58) | FABP4FABP5FABP3TP53HTT | |
| SCHEMBL5665479 | 0.87 | FABP4 (0.62) | FABP4FABP5FABP3TP53HTT | |
| SCHEMBL5838988 | 0.87 | FABP4 (0.62) | FABP4FABP5FABP3TP53HTT | |
| SCHEMBL9445119 | 0.86 | TP53 (0.65) | FABP4FABP5TP53HTTHIF1A | |
| SCHEMBL5662912 | 0.82 | FABP4 (0.67) | FABP4FABP5FABP3TP53HTT | |
| SCHEMBL5663261 | 0.81 | FABP4 (0.74) | FABP4FABP5FABP3TP53HTT | |
| SCHEMBL5840313 | 0.80 | FABP4 (0.65) | FABP4FABP5FABP3TP53HTT | |
| SCHEMBL8622450 | 0.78 | HIF1A (0.52) | TP53HTTHIF1AMRGPRX4ALDH1A1 | |
| SCHEMBL8622454 | 0.78 | HIF1A (0.52) | TP53HTTHIF1AMRGPRX4ALDH1A1 | |
| SCHEMBL8624123 | 0.78 | HIF1A (0.57) | TP53HTTHIF1AMRGPRX4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6984645-B2 | Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-01-10 | — | — | US | disclosed |
| US-20030225091-A1 | Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein | BRISTOL-MYERS SQUIBB COMPANY | 2003-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225091-A1 | Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein | FABP4, FABP2, FABP1 | FABP4 1/4885FABP5 4/4885FABP3 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.