Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 5/20 | 0.65 |
| ▸ | FABP5 | Q01469 | 5/20 | 0.65 |
| ▸ | FABP3 | P05413 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5663261 | 0.92 | FABP4 (0.74) | FABP4FABP5FABP3HTTTP53 | |
| SCHEMBL5662630 | 0.85 | TP53 (0.74) | FABP4FABP5FABP3HTTTP53 | |
| SCHEMBL5838308 | 0.84 | FABP4 (0.63) | FABP4FABP5FABP3HTTTP53 | |
| SCHEMBL5840021 | 0.83 | FABP4 (0.62) | FABP4FABP5FABP3HTTTP53 | |
| SCHEMBL5839103 | 0.83 | FABP4 (0.61) | FABP4FABP5FABP3HTTTP53 | |
| SCHEMBL5838836 | 0.82 | FABP4 (0.61) | FABP4FABP5FABP3HTTTP53 | |
| SCHEMBL5662912 | 0.82 | FABP4 (0.67) | FABP4FABP5FABP3HTTTP53 | |
| SCHEMBL5663904 | 0.81 | FABP4 (0.87) | FABP4FABP5FABP3HTTTP53 | |
| SCHEMBL1388012 | 0.81 | ALDH1A1 (0.68) | HTTTP53MRGPRX4NPC1RAB9A | |
| SCHEMBL1388155 | 0.81 | HTT (0.77) | FABP4FABP5FABP3HTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6984645-B2 | Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-01-10 | — | — | US | disclosed |