Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 16/20 | 0.39 |
| ▸ | CA2 | P00918 | 16/20 | 0.39 |
| ▸ | CA9 | Q16790 | 15/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | CA7 | P43166 | 5/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.39 |
| ▸ | CA3 | P07451 | 4/20 | 0.39 |
| ▸ | CA4 | P22748 | 4/20 | 0.39 |
| ▸ | CA6 | P23280 | 4/20 | 0.39 |
| ▸ | CA5A | P35218 | 4/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5838756 | 0.89 | TSHR (0.57) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL10890011 | 0.89 | TSHR (0.57) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL563993 | 0.86 | TSHR (0.60) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL11401918 | 0.82 | TSHR (0.71) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL1283997 | 0.82 | TSHR (0.71) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL29018669 | 0.82 | TSHR (0.71) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL5838934 | 0.81 | — | — | |
| SCHEMBL564550 | 0.81 | TSHR (0.52) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL5461800 | 0.80 | CA1 (0.59) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL5464695 | 0.80 | CA1 (0.59) | TSHRKDM4EUSP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7033765-B1 | Site-specific drug delivery | TORONTO RESEARCH CHEMICALS, INC. (CA) | 2006-04-25 | — | — | US | disclosed |
| US-20060009375-A1 | Site-specific drug delivery | TORONTO RESEARCH CHEMICALS, INC. (CA) | 2006-01-12 | — | — | US | disclosed |
| EP-0966304-B1 | SITE-SPECIFIC DRUG DELIVERY | DIME DAVID S (CA) | 2005-05-25 | — | — | EP | disclosed |
| EP-0966304-A1 | SITE-SPECIFIC DRUG DELIVERY | Dime, David S. (CA) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998036777-A1 | SITE-SPECIFIC DRUG DELIVERY | DIME DAVID S (CA) | 1998-08-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060009375-A1 | Site-specific drug delivery | ABCG2, ABCB1, DHFR | TSHR 3453/4885KDM4E 3840/4885USP2 2539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.