Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2527145 | 1.00 | STAT3 (0.41) | STAT3TSHRMAPK1ALDH1A1KDM4E | |
| SCHEMBL584986 | 0.91 | KDM4E (0.41) | STAT3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL585403 | 0.90 | GSK3B (0.41) | STAT3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL2837867 | 0.90 | GSK3B (0.41) | STAT3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL2531161 | 0.89 | HSD17B10 (0.45) | TSHRALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL584762 | 0.89 | HSD17B10 (0.45) | TSHRALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL585458 | 0.86 | STAT3 (0.39) | STAT3TSHRMAPK1ALDH1A1KDM4E | |
| SCHEMBL2840348 | 0.82 | GSK3B (0.38) | STAT3TSHRMAPK1ALDH1A1KDM4E | |
| SCHEMBL2838588 | 0.81 | ADRB2 (0.46) | STAT3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL584972 | 0.81 | ADRB2 (0.46) | STAT3ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102217-B1 | 4- (2-OXO-OXAZOLIDIN-3YL)-PHENOXYMETHYLE DERIVATIVEAS AS ANTIBACTERIALS | ACTELION PHARMACEUTICALS LTD (CH) | 2012-02-15 | — | — | EP | disclosed |