Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2531161 | 1.00 | HSD17B10 (0.45) | HSD17B10KDM4EALDH1A1HPGDPMP22 | |
| SCHEMBL584986 | 0.92 | KDM4E (0.41) | HSD17B10KDM4EALDH1A1HPGDPMP22 | |
| SCHEMBL2527145 | 0.89 | STAT3 (0.41) | HSD17B10KDM4EALDH1A1HPGDPMP22 | |
| SCHEMBL583952 | 0.89 | STAT3 (0.41) | HSD17B10KDM4EALDH1A1HPGDPMP22 | |
| SCHEMBL2845822 | 0.88 | KCNH2 (0.46) | HSD17B10KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL585355 | 0.88 | KCNH2 (0.46) | HSD17B10KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL2838588 | 0.82 | ADRB2 (0.46) | HSD17B10KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL584972 | 0.82 | ADRB2 (0.46) | HSD17B10KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL585403 | 0.79 | GSK3B (0.41) | HSD17B10KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL2837867 | 0.79 | GSK3B (0.41) | HSD17B10KDM4EALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102217-B1 | 4- (2-OXO-OXAZOLIDIN-3YL)-PHENOXYMETHYLE DERIVATIVEAS AS ANTIBACTERIALS | ACTELION PHARMACEUTICALS LTD (CH) | 2012-02-15 | — | — | EP | disclosed |