Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | TRPV2 | Q9Y5S1 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5839056 | 1.00 | SLC6A2 (0.41) | SLC6A2HRH1OPRM1PSEN1ALDH1A1 | |
| SCHEMBL5839590 | 0.82 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL5839706 | 0.81 | PSEN1 (0.33) | SLC6A2HRH1OPRM1PSEN1ALDH1A1 | |
| SCHEMBL5839138 | 0.81 | PSEN1 (0.33) | SLC6A2HRH1OPRM1PSEN1ALDH1A1 | |
| SCHEMBL5838872 | 0.72 | ALOX5 (0.41) | SLC6A2TRPA1LDHACNR1SLC6A4 | |
| SCHEMBL5839458 | 0.72 | ALOX5 (0.41) | SLC6A2TRPA1LDHACNR1SLC6A4 | |
| SCHEMBL5839052 | 0.72 | PSEN1 (0.51) | PSEN1PTPN1 | |
| SCHEMBL5838888 | 0.72 | PSEN1 (0.51) | PSEN1PTPN1 | |
| SCHEMBL5839030 | 0.70 | ALDH1A1 (0.38) | SLC6A2HRH1OPRM1ALDH1A1 | |
| SCHEMBL5839667 | 0.70 | ALDH1A1 (0.38) | SLC6A2HRH1OPRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7115657-B2 | Bifunctional agents possessing antioxidant and antiarrhythmic activity | UNI-PHARMA KLEON TSETIS PHARMACEUTICAL LABORATORIES S.A. (GR) | 2006-10-03 | — | — | US | disclosed |
| EP-1301504-B1 | BIFUNCTIONAL AGENTS POSSESSING ANTIOXIDANT AND ANTIARRHYTHMIC ACTIVITY | UNI PHARMA KLEON TSETIS PHARMACEUTICAL LAB SA (GR) | 2004-11-03 | — | — | EP | disclosed |
| EP-1301504-A1 | BIFUNCTIONAL AGENTS POSSESSING ANTIOXIDANT AND ANTIARRHYTHMIC ACTIVITY | Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. (GR) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002004438-A1 | BIFUNCTIONAL AGENTS POSSESSING ANTIOXIDANT AND ANTIARRHYTHMIC ACTIVITY | UNI-PHARMA KLEON TSETIS PHARMACEUTICAL LABORATORIES S.A. (GR) | 2002-01-17 | — | — | WO | disclosed |