Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.59 |
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.52 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.52 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1097268 | 0.89 | MRGPRX4 (0.53) | PTGER1MRGPRX4APEX1FFAR4MAOB | |
| SCHEMBL5680240 | 0.88 | APEX1 (0.58) | PTGER1APEX1FFAR4FOLH1ALDH1A1 | |
| SCHEMBL5666920 | 0.87 | PARP1 (0.62) | MRGPRX4FFAR4L3MBTL1MAOBSLC1A5 | |
| SCHEMBL9784448 | 0.87 | APEX1 (0.57) | PTGER1APEX1FFAR4FOLH1ALDH1A1 | |
| SCHEMBL8425730 | 0.86 | HTT (0.56) | PTGER1FFAR4L3MBTL1MAOBALDH1A1 | |
| SCHEMBL112903 | 0.84 | SGMS2 (0.66) | PTGER1L3MBTL1FOLH1ALDH1A1KMT2A | |
| SCHEMBL29433417 | 0.84 | SGMS2 (0.66) | PTGER1L3MBTL1FOLH1ALDH1A1KMT2A | |
| SCHEMBL5839101 | 0.83 | ALDH1A1 (0.59) | PTGER1APEX1FOLH1ALDH1A1KMT2A | |
| SCHEMBL1388008 | 0.83 | MRGPRX4 (0.59) | PTGER1MRGPRX4APEX1MAOBLRRK2 | |
| SCHEMBL9951153 | 0.83 | MRGPRX4 (0.63) | PTGER1MRGPRX4MAOBFOLH1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111995567-B | Formamide pyridone iron chelator derivative with potential multi-target anti-AD activity and preparation method and application thereof | 浙江工业大学 | 2022-11-25 | — | — | CN | disclosed |
| CN-111995567-A | Formamide pyridone iron chelator derivative with potential multi-target anti-AD activity and preparation method and application thereof | 浙江工业大学 | 2020-11-27 | — | — | CN | disclosed |
| US-6984645-B2 | Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-01-10 | — | — | US | disclosed |
| US-5034370-A | Reaction product of a salicylic acid derivative with formaldehyde and an aromatic compound | SUMITOMO DUREZ COMPANY, LTD. (JP) | 1991-07-23 | — | — | US | disclosed |