Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.72 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.67 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.65 |
| ▸ | CDK2 | P24941 | 3/20 | 0.65 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.65 |
| ▸ | SCD | O00767 | 1/20 | 0.65 |
| ▸ | ACP1 | P24666 | 1/20 | 0.62 |
| ▸ | CNR1 | P21554 | 1/20 | 0.60 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.60 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.55 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.55 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.54 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.53 |
| ▸ | WNT3A | P56704 | 1/20 | 0.52 |
| ▸ | NQO2 | P16083 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30142626 | 0.85 | KDR (0.65) | KDRGSTO1CCNE1CDK2CDK5 | |
| SCHEMBL24074022 | 0.85 | KDR (0.65) | KDRGSTO1CCNE1CDK2CDK5 | |
| SCHEMBL17632040 | 0.84 | ABL1 (0.62) | KDRGSTO1CCNE1CDK2CDK5 | |
| SCHEMBL17014785 | 0.84 | KDR (0.68) | KDRGSTO1CCNE1CDK2CDK5 | |
| SCHEMBL10252594 | 0.84 | KDR (1.00) | KDRGSTO1CCNE1CDK2CDK5 | |
| SCHEMBL2256136 | 0.84 | KDR (0.72) | KDRGSTO1CCNE1CDK2CDK5 | |
| SCHEMBL12496031 | 0.82 | KDR (0.50) | KDRGSTO1CCNE1CDK2CDK5 | |
| SCHEMBL7518296 | 0.81 | KDR (0.50) | KDRGSTO1CCNE1CDK2CDK5 | |
| SCHEMBL6281775 | 0.81 | CNR1 (0.82) | KDRGSTO1CCNE1CDK2CDK5 | |
| SCHEMBL69753 | 0.81 | CCNE1 (0.74) | KDRGSTO1CCNE1CDK2CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102725287-B | 1,3, 4-oxadiazole-2-carboxamide compounds | PHARMA IP GENERAL INC ASS | 2015-07-01 | — | — | CN | disclosed |
| CN-102725287-A | 1,3, 4-oxadiazole-2-carboxamide compounds | PHARMA IP GENERAL INC ASS | 2012-10-10 | — | — | CN | disclosed |
| US-7037929-B1 | 2-amino-thiazole derivatives, process for their preparation, and their use as antitumor agents | PHARMACIA & UPJOHN S.P.A. (IT) | 2006-05-02 | — | — | US | disclosed |
| EP-1124810-B9 | 2-AMINO-THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA ITALIA SPA (IT) | 2005-12-28 | — | — | EP | disclosed |
| EP-1124810-B1 | 2-AMINO-THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA ITALIA SPA (IT) | 2005-05-04 | — | — | EP | disclosed |