Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 6/20 | 0.37 |
| ▸ | CES2 | O00748 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LSS | P48449 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5993484 | 0.92 | TSHR (0.46) | TSHRLMNATHRBCES1CES2 | |
| SCHEMBL217738 | 0.92 | TSHR (0.46) | TSHRLMNATHRBCES1CES2 | |
| SCHEMBL6577114 | 0.92 | TSHR (0.46) | TSHRLMNATHRBCES1CES2 | |
| SCHEMBL489856 | 0.92 | TSHR (0.46) | TSHRLMNATHRBCES1CES2 | |
| SCHEMBL5575821 | 0.92 | TSHR (0.46) | TSHRLMNATHRBCES1CES2 | |
| SCHEMBL6525154 | 0.92 | TSHR (0.46) | TSHRLMNATHRBCES1CES2 | |
| SCHEMBL1925873 | 0.92 | TSHR (0.46) | TSHRLMNATHRBCES1CES2 | |
| SCHEMBL1506925 | 0.92 | TSHR (0.46) | TSHRLMNATHRBCES1CES2 | |
| SCHEMBL6561911 | 0.92 | TSHR (0.46) | TSHRLMNATHRBCES1CES2 | |
| Silver SCHEMBL8342615 | 0.92 | TSHR (0.46) | TSHRLMNATHRBCES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153805-B2 | Group III-B metal catalyst system | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2006-12-26 | — | — | US | disclosed |
| US-7022783-B2 | synthesis of non tapered, random isoprene-butadiene rubbers with a catalyst made of a Group III-B organometalic compound and an organoaluminum compound and a halogen compound; tire sidewalls with improved cut growth resistance without sacrificing rolling resistance | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2006-04-04 | — | — | US | disclosed |
| US-20060020090-A1 | Group III-B metal catalyst system | THE GOODYEAR TIRE & RUBBER COMPANY | 2006-01-26 | — | — | US | disclosed |
| US-20040186252-A1 | Group III-B metal catalyst system | GOODYEAR TIRE & RUBBER COMPANY, THE | 2004-09-23 | — | — | US | disclosed |
| US-6713565-B2 | HAVING SOLID CORE COMPRISED OF POLYBUTADIENE RUBBER POLYMERIZED IN PRESENCE OF ZIEGLER-NATTA CATALYST AND CARBOXYLIC ACID SHORT STOPPED; HIGH SPEED RESILIENCE | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-03-30 | — | — | US | disclosed |
| US-20030125487-A1 | Copolymerizing isoprene and 1,3- butadiene in a catalyst system of a labile halogen atom compound and a reaction product of an organoaluminum, an alcohol, a silanol, 1,3-butadiene and an orgnaometallic compound | THE GOODYEAR TIRE & RUBBER COMPANY | 2003-07-03 | — | — | US | disclosed |
| US-20030013556-A1 | Golf ball | GOODYEAR TIRE & RUBBER COMPANY, THE | 2003-01-16 | — | — | US | disclosed |
| US-20020137849-A1 | Cis-1,4-polybutadiene that is synthesized utilizing organometallic catalyst systems; polymerization is short-stopped with a fatty alcohol | KERNS MICHAEL LESTER (US) | 2002-09-26 | — | — | US | disclosed |
| EP-0629640-B1 | Process for the synthesis of isoprene-butadiene rubber | GOODYEAR TIRE & RUBBER (US) | 1997-01-08 | — | — | EP | disclosed |
| US-5502126-A | Process for the synthesis of isoprene butadiene rubber | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1996-03-26 | — | — | US | disclosed |
| EP-0629640-A1 | Process for the synthesis of isoprene-butadiene rubber | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1994-12-21 | — | — | EP | disclosed |
| US-5321085-A | Polymerizing diisocyanate and diol in polymeric cement, recovering | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1994-06-14 | — | — | US | disclosed |
| US-5283294-A | Crystalline polymer in rubber elastomer | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1994-02-01 | — | — | US | disclosed |
| US-5283291-A | High modulus rubber composition | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1994-02-01 | — | — | US | disclosed |
| EP-0489216-A1 | High modulus rubber compositions | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1992-06-10 | — | — | EP | disclosed |
| US-5049620-A | High modulus rubber composition | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-09-17 | — | — | US | disclosed |
| EP-0434596-A2 | High modulus rubber composition | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-06-26 | — | — | EP | disclosed |
| EP-0336874-A1 | Inverse phase polymerization | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1989-10-11 | — | — | EP | disclosed |
| EP-0241996-A2 | Molecular weight modifier for use with lanthanide and actinide catalysts | ENICHEM ELASTOMERI S.r.l. (IT) | 1987-10-21 | — | — | EP | disclosed |
| US-4663405-A | ADDITION POLYMERIZATION COORDINATION CATALYSTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1987-05-05 | — | — | US | disclosed |