Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 7/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5841809 | 1.00 | AAK1 (0.39) | AAK1CTSKMAPKAPK2CHRNB2CHRNA4 | |
| SCHEMBL3011552 | 0.79 | AAK1 (0.36) | AAK1 | |
| SCHEMBL3011557 | 0.79 | AAK1 (0.36) | AAK1 | |
| SCHEMBL10399063 | 0.75 | CHRNB2 (0.60) | CHRNB2CHRNA4 | |
| SCHEMBL10399064 | 0.75 | CHRNB2 (0.60) | CHRNB2CHRNA4 | |
| SCHEMBL5199250 | 0.74 | CTSK (0.38) | AAK1CTSKCHRNB2CHRNA4TRPA1 | |
| SCHEMBL5199252 | 0.74 | CTSK (0.38) | AAK1CTSKCHRNB2CHRNA4TRPA1 | |
| SCHEMBL5196577 | 0.69 | CTSK (0.67) | CTSKCA1CA2CA4CA7 | |
| SCHEMBL2837459 | 0.69 | CTSK (0.50) | CTSKCA1CA2CA7 | |
| SCHEMBL2837458 | 0.69 | CTSK (0.50) | CTSKCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060826-B2 | Compounds capable of activating cholinergic receptors | TARGAEEPT, INC. (US) | 2006-06-13 | — | — | US | disclosed |
| US-20050282846-A1 | Compounds capable of activating cholinergic receptors | CALDWELL WILLIAN S | 2005-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282846-A1 | Compounds capable of activating cholinergic receptors | CHRNA4, CHRNB4, CHRM4 | AAK1 2507/4885CTSK 3324/4885MAPKAPK2 994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.