Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.57 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.39 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.39 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.39 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8781830 | 0.83 | CES2 (0.50) | CES2PTPN5ALDH1A1KIF11PDE2A | |
| SCHEMBL6061078 | 0.79 | CES2 (0.56) | CES2PTPN5ALDH1A1KIF11PDE2A | |
| SCHEMBL2001354 | 0.78 | CES2 (0.55) | CES2PTPN5KDM4EALDH1A1HPGD | |
| SCHEMBL10451706 | 0.76 | PDE2A (0.44) | CES2PTPN5ALDH1A1PDE2AMEN1 | |
| SCHEMBL3946265 | 0.76 | PDE2A (0.44) | CES2PTPN5KIF11PDE2ATSHR | |
| SCHEMBL3946738 | 0.76 | CES2 (0.40) | CES2PTPN5KDM4EALDH1A1HPGD | |
| SCHEMBL8883394 | 0.75 | KDM1A (0.44) | CES2KDM4EALDH1A1KIF11MEN1 | |
| SCHEMBL24793381 | 0.75 | CES2 (0.52) | CES2PTPN5KDM4EALDH1A1HPGD | |
| SCHEMBL1538943 | 0.75 | PDE2A (0.56) | CES2PTPN5KIF11PDE2ACYP3A4 | |
| SCHEMBL7601744 | 0.75 | CES2 (0.52) | CES2KIF11PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7038050-B2 | Method for the preparation of highly pure 1-androstene derivatives | HANMI PHARM. CO., LTD. (KR) | 2006-05-02 | — | — | US | claimed |
| EP-1646640-A1 | METHOD FOR THE PREPARATION OF HIGHLY PURE 1-ANDROSTENE DERIVATIVES | Hanmi Pharm. Co., Ltd. (KR) | 2006-04-19 | — | — | EP | claimed |
| US-20050245744-A1 | Method for the preparation of highly pure 1-androstene derivatives | HANMI PHARM. CO., LTLD. (KR) | 2005-11-03 | — | — | US | claimed |
| WO-2005007670-A1 | METHOD FOR THE PREPARATION OF HIGHLY PURE 1-ANDROSTENE DERIVATIVES | HANMI PHARM. CO., LTD. (KR) | 2005-01-27 | — | — | WO | claimed |
| US-5643925-A | COGNITION ACTIVATORS AND NERVE GROWTH FACTORS | SANKYO COMPANY, LIMITED (JP) | 1997-07-01 | — | — | US | disclosed |
| US-5614521-A | NERVE GROWTH FACTOR | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0501656-B1 | New benzene derivatives having (NGF) production-promoting activity | SANKYO CO (JP) | 1997-01-22 | — | — | EP | disclosed |
| EP-0501656-A2 | New benzene derivatives having (NGF) production-promoting activity | Sankyo Company Limited (JP) | 1992-09-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245744-A1 | Method for the preparation of highly pure 1-androstene derivatives | CYP19A1, HSD17B11, CYP17A1 | CES2 536/4885PTPN5 2365/4885KDM4E 4514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.