SCHEMBL7601744

SCHEMBL7601744

Fc1cc(C(F)(F)F)ccc1C(F)(F)F

nearest known ligand 0.52

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.52
KIF11 P52732 10/20 0.50
PDE2A O00408 3/20 0.47
IDO1 P14902 2/20 0.46
KDM1A O60341 1/20 0.46
CYP11B1 P15538 1/20 0.42
CYP11B2 P19099 1/20 0.42
MPL P40238 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4792748 0.84 KIF11 (0.46) KIF11PDE2AKDM1ACYP11B1CYP11B2
SCHEMBL6743200 0.84 PDE2A (0.47) CES2KIF11PDE2AIDO1MPL
SCHEMBL17187086 0.81 KIF11 (0.47) CES2KIF11PDE2AKDM1A
SCHEMBL30417923 0.80 CES2 (0.52) CES2PDE2AIDO1MPL
SCHEMBL2699647 0.80 CES2 (0.52) CES2PDE2AIDO1MPL
SCHEMBL29827588 0.79 PDE2A (0.50) CES2PDE2AIDO1MPL
SCHEMBL2147584 0.79 PDE2A (0.50) CES2PDE2AIDO1MPL
SCHEMBL6061078 0.79 CES2 (0.56) CES2KIF11PDE2A
SCHEMBL7140205 0.78 PDE2A (0.46) CES2PDE2AIDO1MPL
SCHEMBL24836121 0.78 PDE2A (0.47) CES2KIF11PDE2AIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0034731-B1 TRIFLUOROMETHYLBENZYLIC ESTERS, THEIR INTERMEDIATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES BAYER AG (DE) 1985-10-30 EP claimed
US-20020042541-A1 Process for producing bis( trifluoromethyl)benzaldehyde CENTRAL GLASS COMPANY, LIMITED (JP) 2002-04-11 US disclosed
EP-0034731-B1 TRIFLUOROMETHYLBENZYLIC ESTERS, THEIR INTERMEDIATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES BAYER AG (DE) 1985-10-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020042541-A1 Process for producing bis( trifluoromethyl)benzaldehyde BRPF1, PFAS, FLI1 CES2 1070/4885KIF11 4519/4885PDE2A 3339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.