⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246835 | 0.87 | — | — | |
| SCHEMBL3456404 | 0.82 | PLA2G10 (0.31) | — | |
| SCHEMBL6188000 | 0.82 | PLA2G10 (0.31) | — | |
| SCHEMBL1571988 | 0.72 | OPRM1 (0.30) | — | |
| SCHEMBL23793962 | 0.61 | CRBN (0.30) | — | |
| SCHEMBL8903859 | 0.60 | ALDH1A1 (0.33) | — | |
| SCHEMBL2220255 | 0.59 | — | — | |
| SCHEMBL23869840 | 0.59 | GRIN1 (0.33) | — | |
| SCHEMBL23793964 | 0.59 | GRIN1 (0.33) | — | |
| SCHEMBL23869815 | 0.59 | GRIN1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417119-A2 | NO-CARRIER-ADDED NUCLEOPHILIC ÝF-18¨FLUORINATION OF AROMATIC COMPOUNDS | The Regents of The University of California (US) | 2012-02-15 | — | — | EP | disclosed |
| EP-2307337-A2 | NUCLEOPHILIC FLUORINATION OF AROMATIC COMPOUNDS | The Regents Of The University Of California (US) | 2011-04-13 | — | — | EP | disclosed |
| WO-2010117435-A2 | NO-CARRIER-ADDED NUCLEOPHILIC [F-18] FLUORINATION OF AROMATIC COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-10-14 | — | — | WO | disclosed |
| WO-2010008522-A2 | NUCLEOPHILIC FLUORINATION OF AROMATIC COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-01-21 | — | — | WO | disclosed |