Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.33 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5841180 | 1.00 | GRM2 (0.36) | GRM2GRM3MEN1KMT2AENPP2 | |
| SCHEMBL5840380 | 0.85 | GRM2 (0.35) | GRM2GRM3 | |
| SCHEMBL6527774 | 0.85 | GRM2 (0.35) | GRM2GRM3 | |
| SCHEMBL6526776 | 0.85 | GRM2 (0.35) | GRM2GRM3 | |
| SCHEMBL5841128 | 0.85 | GRM2 (0.35) | GRM2GRM3 | |
| SCHEMBL5845592 | 0.83 | GRM2 (0.32) | GRM2GRM3 | |
| SCHEMBL5845057 | 0.83 | GRM2 (0.32) | GRM2GRM3 | |
| SCHEMBL5842164 | 0.80 | GRM2 (0.31) | GRM2GRM3 | |
| SCHEMBL29484698 | 0.80 | GRM2 (0.39) | GRM2GRM3 | |
| SCHEMBL5841850 | 0.80 | GRM2 (0.39) | GRM2GRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7038077-B2 | Prodrugs of excitatory amino acids | ELI LILLY AND COMPANY (US) | 2006-05-02 | — | — | US | disclosed |