Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5845057 | 1.00 | GRM2 (0.32) | GRM2GRM3LMNAKDM4EALDH1A1 | |
| SCHEMBL6527774 | 0.84 | GRM2 (0.35) | GRM2GRM3 | |
| SCHEMBL5840380 | 0.84 | GRM2 (0.35) | GRM2GRM3 | |
| SCHEMBL6526776 | 0.84 | GRM2 (0.35) | GRM2GRM3 | |
| SCHEMBL5841128 | 0.84 | GRM2 (0.35) | GRM2GRM3 | |
| SCHEMBL5842801 | 0.83 | GRM2 (0.36) | GRM2GRM3 | |
| SCHEMBL5841180 | 0.83 | GRM2 (0.36) | GRM2GRM3 | |
| SCHEMBL5842164 | 0.80 | GRM2 (0.31) | GRM2GRM3 | |
| SCHEMBL5841850 | 0.78 | GRM2 (0.39) | GRM2GRM3 | |
| SCHEMBL29484698 | 0.78 | GRM2 (0.39) | GRM2GRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7038077-B2 | Prodrugs of excitatory amino acids | ELI LILLY AND COMPANY (US) | 2006-05-02 | — | — | US | disclosed |