Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 14/20 | 0.62 |
| ▸ | HSD17B2 | P37059 | 13/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.62 |
| ▸ | ESR1 | P03372 | 3/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21312572 | 0.98 | HSD17B1 (0.60) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL21312574 | 0.92 | HSD17B1 (0.61) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL21312573 | 0.88 | HSD17B1 (0.67) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL2239504 | 0.85 | CA12 (0.58) | HSD17B1HSD17B2CYP3A4CYP2C9CA12 | |
| SCHEMBL31281467 | 0.85 | CA12 (0.58) | HSD17B1HSD17B2CYP3A4CYP2C9CA12 | |
| SCHEMBL4671659 | 0.84 | HSD17B1 (0.74) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL69369 | 0.83 | HSD17B1 (0.88) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL29551999 | 0.83 | HSD17B1 (0.88) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL4673713 | 0.81 | HSD17B1 (0.76) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL21312571 | 0.81 | ESR1 (0.61) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6984716-B2 | Phosphorus-containing compound | CHANG CHUN PLASTICS CO., LTD. (TW) | 2006-01-10 | — | — | US | disclosed |
| US-20040077825-A1 | Phosphorus-containing compound | CHANG CHUN PLASTICS CO., LTD. (TW) | 2004-04-22 | — | — | US | disclosed |