Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 12/20 | 0.76 |
| ▸ | HSD17B2 | P37059 | 11/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.68 |
| ▸ | ESR1 | P03372 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.59 |
| ▸ | BCR | P11274 | 1/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.56 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4671659 | 0.96 | HSD17B1 (0.74) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL21312574 | 0.90 | HSD17B1 (0.61) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL4431853 | 0.89 | ESR1 (0.70) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL21312571 | 0.88 | ESR1 (0.61) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL70625 | 0.87 | HSD17B1 (1.00) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL29404406 | 0.87 | HSD17B1 (1.00) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL7129229 | 0.87 | HSD17B1 (1.00) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL1180998 | 0.87 | HSD17B1 (1.00) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL21312573 | 0.86 | HSD17B1 (0.67) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| Hydrogen Sulfide SCHEMBL23879303 | 0.85 | HSD17B1 (0.95) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881815-B2 | Method for the preparation poly(etherimide)s | GENERAL ELECTRIC COMPANY (US) | 2005-04-19 | — | — | US | claimed |
| EP-1458791-A1 | METHODS FOR THE PREPARATION OF POLY(ETHERIMIDES)S | GENERAL ELECTRIC COMPANY (US) | 2004-09-22 | — | — | EP | claimed |
| US-20040063897-A1 | Method for the preparation poly(etherimide)s | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2004-04-01 | — | — | US | claimed |
| US-6590108-B1 | Transimidation of bis(imide) in presence of phthalic anhydride having substituent selected from group consisting of nitro, bromo, fluoro and chloro, to yield dianhydride | GENERAL ELECTRIC COMPANY | 2003-07-08 | — | — | US | claimed |
| WO-2003050165-A1 | METHODS FOR THE PREPARATION OF POLY(ETHERIMIDES)S | GENERAL ELECTRIC COMPANY (US) | 2003-06-19 | — | — | WO | claimed |
| US-6498224-B1 | SOLUTION POLYMERIZATION OF A DIANHYDRIDE AND A DIAMINE WHICH ELIMINATES THE NITRATION STEP; HIGH HEAT ENGINEERING PLASTICS | GENERAL ELECTRIC COMPANY | 2002-12-24 | — | — | US | claimed |
| EP-1403303-B1 | Methods for the preparation of poly(etherimide)s | GEN ELECTRIC (US) | 2008-08-20 | — | — | EP | disclosed |
| EP-1458791-B1 | METHODS FOR THE PREPARATION OF POLY(ETHERIMIDES)S | GEN ELECTRIC (US) | 2006-11-29 | — | — | EP | disclosed |
| US-6881815-B2 | Method for the preparation poly(etherimide)s | GENERAL ELECTRIC COMPANY (US) | 2005-04-19 | — | — | US | disclosed |
| EP-1458791-A1 | METHODS FOR THE PREPARATION OF POLY(ETHERIMIDES)S | GENERAL ELECTRIC COMPANY (US) | 2004-09-22 | — | — | EP | disclosed |
| US-20040063897-A1 | Method for the preparation poly(etherimide)s | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2004-04-01 | — | — | US | disclosed |
| EP-1403303-A1 | Methods for the preparation of poly(etherimide)s | General Electric Company (US) | 2004-03-31 | — | — | EP | disclosed |
| US-6590108-B1 | Transimidation of bis(imide) in presence of phthalic anhydride having substituent selected from group consisting of nitro, bromo, fluoro and chloro, to yield dianhydride | GENERAL ELECTRIC COMPANY | 2003-07-08 | — | — | US | disclosed |
| WO-2003050165-A1 | METHODS FOR THE PREPARATION OF POLY(ETHERIMIDES)S | GENERAL ELECTRIC COMPANY (US) | 2003-06-19 | — | — | WO | disclosed |
| US-6498224-B1 | SOLUTION POLYMERIZATION OF A DIANHYDRIDE AND A DIAMINE WHICH ELIMINATES THE NITRATION STEP; HIGH HEAT ENGINEERING PLASTICS | GENERAL ELECTRIC COMPANY | 2002-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063897-A1 | Method for the preparation poly(etherimide)s | FHIT, PBRM1, PMAIP1 | HSD17B1 2281/4885HSD17B2 2364/4885CYP3A4 1074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.