Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 19/20 | 0.75 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.75 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.75 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5843322 | 0.86 | OPRK1 (0.77) | OPRK1CYP2D6OPRD1OPRM1CYP3A4 | |
| SCHEMBL5844315 | 0.86 | OPRK1 (1.00) | OPRK1CYP2D6OPRD1OPRM1CYP3A4 | |
| SCHEMBL5844312 | 0.86 | OPRK1 (1.00) | OPRK1CYP2D6OPRD1OPRM1CYP3A4 | |
| SCHEMBL5843674 | 0.81 | OPRK1 (1.00) | OPRK1CYP2D6OPRD1OPRM1CYP3A4 | |
| SCHEMBL5843678 | 0.81 | OPRK1 (1.00) | OPRK1CYP2D6OPRD1OPRM1CYP3A4 | |
| Hydrochloric Acid SCHEMBL5842170 | 0.79 | OPRK1 (0.98) | OPRK1CYP2D6OPRD1OPRM1CYP3A4 | |
| Hydrochloric Acid SCHEMBL5842166 | 0.79 | OPRK1 (0.98) | OPRK1CYP2D6OPRD1OPRM1CYP3A4 | |
| SCHEMBL6478413 | 0.78 | OPRK1 (0.77) | OPRK1CYP2D6OPRD1OPRM1CYP3A4 | |
| SCHEMBL6347072 | 0.78 | OPRK1 (0.72) | OPRK1CYP2D6OPRD1OPRM1CYP3A4 | |
| SCHEMBL17870633 | 0.78 | OPRK1 (1.00) | OPRK1CYP2D6OPRD1OPRM1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6992193-B2 | Sulfonylamino phenylacetamide derivatives and methods of their use | ADOLOR CORPORATION (US) | 2006-01-31 | — | — | US | disclosed |
| US-20040254156-A1 | Sulfonylamino phenylacetamide derivatives and methods of their use | CALIXA THERAPEUTICS, INC. | 2004-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254156-A1 | Sulfonylamino phenylacetamide derivatives and methods of their use | CYP2E1, CYP2D6, CYP3A43 | OPRK1 14/4885CYP2D6 2/4885OPRD1 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.