Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5845279 | 0.87 | ALOX15 (0.52) | ALOX15CYP3A4HSD17B10ALDH1A1ESR2 | |
| SCHEMBL18203013 | 0.84 | TDP1 (0.54) | ALOX15CYP3A4HSD17B10ALDH1A1ESR2 | |
| SCHEMBL5843853 | 0.83 | CYP3A4 (0.55) | ALOX15CYP3A4HSD17B10ALDH1A1ESR2 | |
| SCHEMBL5842729 | 0.83 | ALOX15 (0.55) | ALOX15CYP3A4HSD17B10ALDH1A1TDP1 | |
| SCHEMBL5843781 | 0.80 | CYP3A4 (0.52) | ALOX15CYP3A4HSD17B10ALDH1A1ESR2 | |
| SCHEMBL5843762 | 0.80 | ALOX15 (0.52) | ALOX15CYP3A4HSD17B10ALDH1A1ESR2 | |
| SCHEMBL21021367 | 0.79 | ALDH1A1 (0.55) | ALOX15CYP3A4HSD17B10ALDH1A1TDP1 | |
| SCHEMBL5845352 | 0.79 | ALOX15 (0.55) | ALOX15CYP3A4HSD17B10ALDH1A1ESR2 | |
| SCHEMBL6376797 | 0.79 | ALOX15 (0.37) | ALOX15CYP3A4HSD17B10ALDH1A1TDP1 | |
| SCHEMBL5845416 | 0.77 | CYP3A4 (0.63) | ALOX15CYP3A4HSD17B10ALDH1A1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122061-B2 | Agents for dyeing keratin fibers, containing 4-aminobiphenyl-3-ol-derivatives | WELLA AG (DE) | 2006-10-17 | — | — | US | claimed |
| US-7122061-B2 | Agents for dyeing keratin fibers, containing 4-aminobiphenyl-3-ol-derivatives | WELLA AG (DE) | 2006-10-17 | — | — | US | disclosed |
| EP-1562539-A1 | AGENTS FOR DYEING KERATIN FIBERS, CONTAINING 4-AMINO-BIPHENYL-3-OL-DERIVATIVES | Wella Aktiengesellschaft (DE) | 2005-08-17 | — | — | EP | disclosed |
| US-20050155160-A1 | Agents for dyeing keratin fibers, containing 4-amino-biphenyl-3-ol-derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2005-07-21 | — | — | US | disclosed |
| WO-2004041226-A1 | AGENTS FOR DYEING KERATIN FIBERS, CONTAINING 4-AMINO-BIPHENYL-3-OL-DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-05-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050155160-A1 | Agents for dyeing keratin fibers, containing 4-amino-biphenyl-3-ol-derivatives | KRT18, CBR3, CCNB3 | ALOX15 3006/4885CYP3A4 835/4885HSD17B10 913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.