Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.37 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3269762 | 1.00 | TRPA1 (0.37) | TRPA1TRPM8SLC10A1CYP19A1EPHX1 | |
| SCHEMBL6907615 | 1.00 | TRPA1 (0.37) | TRPA1TRPM8SLC10A1CYP19A1EPHX1 | |
| SCHEMBL28317324 | 0.86 | TRPA1 (0.35) | TRPA1TRPM8 | |
| SCHEMBL4733415 | 0.86 | TRPA1 (0.35) | TRPA1TRPM8 | |
| SCHEMBL28252261 | 0.86 | TRPA1 (0.35) | TRPA1TRPM8 | |
| SCHEMBL5926940 | 0.85 | TRPA1 (0.37) | TRPA1TRPM8 | |
| Water SCHEMBL6762719 | 0.84 | TRPA1 (0.34) | TRPA1TRPM8 | |
| SCHEMBL4885149 | 0.84 | TRPA1 (0.36) | TRPA1TRPM8 | |
| SCHEMBL8088736 | 0.84 | TRPA1 (0.36) | TRPA1TRPM8 | |
| SCHEMBL27824250 | 0.84 | TRPA1 (0.36) | TRPA1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2168957-B1 | Alkyl-substituted tetrahydropyranes as aromatic materials | SYMRISE AG (DE) | 2012-02-15 | — | — | EP | disclosed |
| EP-2168957-A2 | Alkyl-substituted tetrahydropyranes as aromatic materials | Symrise GmbH & Co. KG (DE) | 2010-03-31 | — | — | EP | disclosed |