SCHEMBL5843592

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5845462	0.83	CYP3A4 (0.53)	CYP3A4ALOX15HSD17B10APPESR2
	SCHEMBL5843815	0.83	CYP3A4 (0.53)	CYP3A4ALOX15HSD17B10APPBACE1
	SCHEMBL5842547	0.83	CYP3A4 (0.57)	CYP3A4ALOX15HSD17B10APPESR2
	SCHEMBL5843816	0.81	CYP3A4 (0.50)	CYP3A4ALOX15HSD17B10APPESR2
	SCHEMBL5843610	0.81	CYP3A4 (0.50)	CYP3A4ALOX15HSD17B10APPESR2
	SCHEMBL5844791	0.81	CYP3A4 (0.50)	CYP3A4ALOX15HSD17B10APPBACE1
	SCHEMBL6375239	0.80	CYP3A4 (0.42)	CYP3A4ALOX15HSD17B10APPESR2
	SCHEMBL5844230	0.78	ALOX15 (0.59)	CYP3A4ALOX15HSD17B10APPESR2
	SCHEMBL5843378	0.77	CYP3A4 (0.50)	CYP3A4ALOX15HSD17B10ESR2ALDH1A1
	SCHEMBL20056591	0.77	ESR2 (0.54)	CYP3A4APPESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.