Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5843610 | 0.92 | CYP3A4 (0.50) | CYP3A4ALOX15HSD17B10ALDH1A1ABL1 | |
| SCHEMBL5843520 | 0.92 | CYP3A4 (0.50) | CYP3A4ALOX15HSD17B10ALOX5APFEN1 | |
| SCHEMBL5843592 | 0.80 | CYP3A4 (0.50) | CYP3A4ALOX15HSD17B10ALDH1A1PTGS1 | |
| SCHEMBL5843816 | 0.80 | CYP3A4 (0.50) | CYP3A4ALOX15HSD17B10PTGS1PTGS2 | |
| SCHEMBL5843378 | 0.77 | CYP3A4 (0.50) | CYP3A4ALOX15HSD17B10ALDH1A1ALOX5AP | |
| SCHEMBL5843815 | 0.76 | CYP3A4 (0.53) | CYP3A4ALOX15HSD17B10CNR2ALOX5AP | |
| SCHEMBL5844303 | 0.76 | CYP3A4 (0.53) | CYP3A4ALOX15HSD17B10ALDH1A1CNR2 | |
| SCHEMBL5845462 | 0.76 | CYP3A4 (0.53) | CYP3A4ALOX15HSD17B10ALDH1A1CNR2 | |
| SCHEMBL5843391 | 0.76 | ALOX15 (0.57) | CYP3A4ALOX15HSD17B10ALDH1A1ALOX5AP | |
| SCHEMBL5842547 | 0.76 | CYP3A4 (0.57) | CYP3A4ALOX15HSD17B10ALDH1A1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050155160-A1 | Agents for dyeing keratin fibers, containing 4-amino-biphenyl-3-ol-derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2005-07-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050155160-A1 | Agents for dyeing keratin fibers, containing 4-amino-biphenyl-3-ol-derivatives | KRT18, CBR3, CCNB3 | CYP3A4 835/4885ALOX15 3006/4885HSD17B10 913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.