Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 20/20 | 0.42 |
| ▸ | IKBKE | Q14164 | 13/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17289902 | 0.75 | TBK1 (0.47) | TBK1IKBKE | |
| SCHEMBL17630225 | 0.72 | TBK1 (0.56) | TBK1IKBKE | |
| SCHEMBL10926986 | 0.72 | CSNK2A1 (0.36) | — | |
| SCHEMBL24928876 | 0.72 | TBK1 (0.41) | TBK1IKBKE | |
| SCHEMBL5843092 | 0.72 | XDH (0.34) | — | |
| SCHEMBL15321117 | 0.71 | TBK1 (0.53) | TBK1IKBKE | |
| SCHEMBL20472554 | 0.71 | TBK1 (0.46) | TBK1IKBKE | |
| SCHEMBL22470817 | 0.71 | TBK1 (0.51) | TBK1IKBKE | |
| SCHEMBL1667546 | 0.71 | TBK1 (0.51) | TBK1IKBKE | |
| SCHEMBL15782897 | 0.71 | SYK (0.58) | TBK1IKBKE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7012041-B2 | Phenylpyridazinones | BAYER AG (DE) | 2006-03-14 | — | — | US | disclosed |
| EP-1120411-B1 | 4-Aryl-1,2,4-triazolidinedione derivatives and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2004-09-22 | — | — | EP | disclosed |
| US-20030208073-A1 | Substituted N-aryl nitrogen-containing heterocyclic compounds | LINKER KARL-HEINZ (DE) | 2003-11-06 | — | — | US | disclosed |
| US-20030119673-A1 | Phenylpyridazinones | LINKER KARL-HEINZ (DE) | 2003-06-26 | — | — | US | disclosed |
| US-6551963-B1 | For controlling unwanted vegetation | BAYER AKTIENGESELLSCHAFT (DE) | 2003-04-22 | — | — | US | disclosed |
| US-6426318-B1 | KILLING WEEDS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-30 | — | — | US | disclosed |
| EP-1120411-A2 | 4-Aryl-1,2,4-triazolidinedione derivatives and their use as herbicides | BAYER AG (DE) | 2001-08-01 | — | — | EP | disclosed |
| EP-1070055-A1 | SUBSTITUTED PHENYL PYRIDAZINONES | Bayer Aktiengesellschaft (DE) | 2001-01-24 | — | — | EP | disclosed |
| US-6162765-A | Substituted N-aryl nitrogen-containing heterocyclic compounds | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-19 | — | — | US | disclosed |
| US-6159903-A | Substituted 2-aryl-1,2,4-triazine-3,5-di(thi)ones as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-12 | — | — | US | disclosed |
| WO-2000008000-A1 | USE OF SUBSTITUTED TRIAZINONES AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-02-17 | — | — | WO | disclosed |
| WO-1999052878-A1 | SUBSTITUTED PHENYL PYRIDAZINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-10-21 | — | — | WO | disclosed |
| EP-0882027-A1 | SUBSTITUTED 2-ARYL-1,2,4-TRIAZINE-3,5-DI(THI)ONES AS HERBICIDES | BAYER AG (DE) | 1998-12-09 | — | — | EP | disclosed |
| EP-0832072-A1 | PHENYLPYRIDAZINONES | BAYER AG (DE) | 1998-04-01 | — | — | EP | disclosed |
| EP-0797573-A1 | 3-ARYL-1,2,4-TRIAZOLE DERIVATIVES WITH HERBICIDAL PROPERTIES | BAYER AG (DE) | 1997-10-01 | — | — | EP | disclosed |
| WO-1997030980-A1 | SUBSTITUTED 2-ARYL-1,2,4-TRIAZINE-3,5-DI(THI)ONES AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-08-28 | — | — | WO | disclosed |
| WO-1997026248-A1 | SUBSTITUTED N-ARYL NITROGEN HETEROCYCLIC COMPOUNDS AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-07-24 | — | — | WO | disclosed |
| WO-1997005117-A1 | SUBSTITUTED 1-PHENYLURACIL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-13 | — | — | WO | disclosed |
| WO-1996039392-A1 | PHENYLPYRIDAZINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-12 | — | — | WO | disclosed |
| WO-1996018618-A1 | 3-ARYL-1,2,4-TRIAZOLE DERIVATIVES WITH HERBICIDAL PROPERTIES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030208073-A1 | Substituted N-aryl nitrogen-containing heterocyclic compounds | NAT1, CYP1B1, CYP1A1 | TBK1 4506/4885IKBKE 1744/4885 |
| US-20030119673-A1 | Phenylpyridazinones | CYP2D6, CYP1A1, CYP1B1 | TBK1 4803/4885IKBKE 2795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.