SCHEMBL584382

SCHEMBL584382

C=CCc1ccc(-c2ccccc2CC=C)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 9/20 0.48
GABRB2 P47870 9/20 0.48
CNR2 P34972 5/20 0.46
ALOX5 P09917 5/20 0.46
MAPT P10636 3/20 0.46
MEN1 O00255 2/20 0.46
GAA P10253 2/20 0.46
CNR1 P21554 2/20 0.46
KMT2A Q03164 2/20 0.46
POLB P06746 1/20 0.46
GABRB1 P18505 1/20 0.46
RXRA P19793 1/20 0.46
GABRA5 P31644 1/20 0.46
GABRA3 P34903 1/20 0.46
GABRA2 P47869 1/20 0.46
ACE2 Q9BYF1 1/20 0.46
SIRT3 Q9NTG7 1/20 0.46
AKR1B1 P15121 2/20 0.45
ALDH1A1 P00352 2/20 0.41
CYP3A4 P08684 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL170787 0.86 DPP4 (0.54) GABRA1GABRB2KMT2AAKR1B1ALDH1A1
SCHEMBL6537109 0.86 GABRA1 (0.59) GABRA1GABRB2CNR2ALOX5MAPT
Water SCHEMBL821345 0.84 DPP4 (0.52) GABRA1GABRB2KMT2AAKR1B1ALDH1A1
SCHEMBL28758160 0.84 DPP4 (0.52) GABRA1GABRB2KMT2AAKR1B1ALDH1A1
Biphenyl SCHEMBL7928631 0.84 DPP4 (0.52) GABRA1GABRB2KMT2AAKR1B1ALDH1A1
SCHEMBL27886719 0.84 GABRA1 (0.47) GABRA1GABRB2CNR2ALOX5MAPT
SCHEMBL27684898 0.84 DPP4 (0.52) GABRA1GABRB2KMT2AAKR1B1ALDH1A1
SCHEMBL27677647 0.83 GABRA1 (0.56) GABRA1GABRB2CNR2ALOX5MAPT
SCHEMBL2362466 0.81 GABRA1 (0.61) GABRA1GABRB2MAPTMEN1GAA
SCHEMBL29900352 0.81 GABRA1 (0.61) GABRA1GABRB2MAPTMEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1746116-B1 COPOLYMER, GRAFT COPOLYMER, GRAFT COPOLYMER PARTICLE, FLAME RETARDANT, AND RESIN COMPOSITION KANEKA CORP (JP) 2011-07-06 EP claimed
US-8742014-B2 Liquid resin composition and cured product using the liquid resin composition KANEKA CORPORATION (JP) 2014-06-03 US disclosed
EP-2189502-B1 LIQUID RESIN COMPOSITION AND CURED PRODUCT USING THE LIQUID RESIN COMPOSITION KANEKA CORP (JP) 2013-05-15 EP disclosed
EP-1832613-B9 GRAFT COPOLYMER, METHOD FOR PRODUCING SAME AND RESIN COMPOSITION CONTAINING SUCH GRAFT COPOLYMER KANEKA CORP (JP) 2012-08-29 EP disclosed
EP-1832613-B1 GRAFT COPOLYMER, METHOD FOR PRODUCING SAME AND RESIN COMPOSITION CONTAINING SUCH GRAFT COPOLYMER KANEKA CORP (JP) 2012-02-15 EP disclosed
EP-1746116-B1 COPOLYMER, GRAFT COPOLYMER, GRAFT COPOLYMER PARTICLE, FLAME RETARDANT, AND RESIN COMPOSITION KANEKA CORP (JP) 2011-07-06 EP disclosed
US-7855257-B2 Copolymer, graft copolymer, graft copolymer particles, flame retardant, and resin composition KANEKA CORPORATION (JP) 2010-12-21 US disclosed
US-20100204404-A1 LIQUID RESIN COMPOSITION AND CURED PRODUCT USING THE LIQUID RESIN COMPOSITION KANEKA CORPORATION 2010-08-12 US disclosed
EP-2189502-A1 LIQUID RESIN COMPOSITION AND CURED PRODUCT USING THE LIQUID RESIN COMPOSITION Kaneka Corporation (JP) 2010-05-26 EP disclosed
US-20080085975-A1 Graft Copolymer, Method For Producing The Same And Resin Composition Containing The Graft Copolymer KANEKA CORPORATION (JP) 2008-04-10 US disclosed
US-20070219319-A1 Copolymer, Graft Copolymer, Graft Copolymer Particles, Flame Retardant, and Resin Composition KANEKA CORPORATION 2007-09-20 US disclosed
EP-1832613-A1 GRAFT COPOLYMER, METHOD FOR PRODUCING SAME AND RESIN COMPOSITION CONTAINING SUCH GRAFT COPOLYMER Kaneka Corporation (JP) 2007-09-12 EP disclosed
EP-1746116-A1 COPOLYMER, GRAFT COPOLYMER, GRAFT COPOLYMER PARTICLE, FLAME RETARDANT, AND RESIN COMPOSITION Kaneka Corporation (JP) 2007-01-24 EP disclosed