Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.62 |
| ▸ | TNKS | O95271 | 1/20 | 0.55 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.55 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.55 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.55 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.55 |
| ▸ | F10 | P00742 | 4/20 | 0.53 |
| ▸ | F2 | P00734 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2901873 | 0.87 | AKR1C3 (0.57) | F10F2L3MBTL1SMN1; SMN2 | |
| SCHEMBL29503138 | 0.78 | PARP1 (1.00) | PARP1TNKSPARP15PARP14PARP10 | |
| SCHEMBL283787 | 0.78 | PARP1 (1.00) | PARP1TNKSPARP15PARP14PARP10 | |
| SCHEMBL13687397 | 0.77 | PARP10 (0.78) | PARP1TNKSPARP15PARP14PARP10 | |
| Hydrochloric Acid SCHEMBL407554 | 0.76 | PARP1 (0.96) | PARP1TNKSPARP15PARP14PARP10 | |
| Hydrochloric Acid SCHEMBL4377519 | 0.76 | PARP1 (0.96) | PARP1TNKSPARP15PARP14PARP10 | |
| SCHEMBL14189347 | 0.75 | L3MBTL1 (0.61) | L3MBTL1SMN1; SMN2MEN1KMT2ACYP1A2 | |
| SCHEMBL30466441 | 0.75 | AKR1C3 (0.70) | TNKSPARP15PARP14PARP10TNKS2 | |
| SCHEMBL9767808 | 0.74 | L3MBTL1 (0.75) | L3MBTL1SMN1; SMN2MEN1KMT2ACYP1A2 | |
| SCHEMBL9694796 | 0.74 | L3MBTL1 (0.59) | L3MBTL1SMN1; SMN2CYP1A2CYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109243-B2 | Inhibitors of cathepsin S | IRM LLC (BM) | 2006-09-19 | — | — | US | disclosed |