Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104603 | 0.90 | CA1 (0.30) | — | |
| SCHEMBL10581273 | 0.75 | — | — | |
| SCHEMBL108800 | 0.71 | ADRB2 (0.45) | TSHRALDH1A1 | |
| Alcohol SCHEMBL8706521 | 0.69 | TSHR (0.50) | TSHRALDH1A1HSD17B10 | |
| SCHEMBL20513492 | 0.69 | — | — | |
| SCHEMBL20513613 | 0.69 | — | — | |
| Alcohol SCHEMBL10900944 | 0.67 | — | — | |
| SCHEMBL20513589 | 0.67 | THRB (0.47) | TSHR | |
| SCHEMBL20513609 | 0.67 | THRB (0.47) | TSHR | |
| SCHEMBL1361773 | 0.67 | THRB (0.47) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1653256-B1 | FLUID COLLOID CRYSTAL AND PROCESS FOR PRODUCING THREE-DIMENSIONAL ALIGNED PARTICLE MASS THEREFROM | SOKEN KAGAKU KK (JP) | 2012-02-15 | — | — | EP | disclosed |
| US-7527829-B2 | Fluid colloid crystal and process for producing three-dimensional aligned particle mass therefrom | SOKEN CHEMICAL & ENGINEERING CO., LTD. (JP) | 2009-05-05 | — | — | US | disclosed |
| US-20060182968-A1 | Fluid colloid crystal and process for producing three-dimensionsl aligned particle mass therefrom | SOKEN CHEMICAL & ENGINEERING CO., LTD. (JP) | 2006-08-17 | — | — | US | disclosed |
| EP-1653256-A1 | FLUID COLLOID CRYSTAL AND PROCESS FOR PRODUCING THREE-DIMENSIONAL ALIGNED PARTICLE MASS THEREFROM | SOKEN CHEMICAL & ENGINEERING CO. LTD., (JP) | 2006-05-03 | — | — | EP | disclosed |