Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 8/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5764374 | 0.73 | CRHR1 (0.36) | CRHR1 | |
| SCHEMBL5842827 | 0.72 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL5763890 | 0.68 | DPP4 (0.38) | CRHR1 | |
| SCHEMBL7433769 | 0.68 | CRHR1 (0.55) | CRHR1 | |
| SCHEMBL6093298 | 0.65 | CRHR1 (0.35) | CRHR1 | |
| SCHEMBL11016252 | 0.65 | CRHR1 (0.41) | CRHR1 | |
| SCHEMBL5845879 | 0.64 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL6428085 | 0.64 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL5843268 | 0.64 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL5844199 | 0.64 | CRHR1 (0.47) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067664-B1 | Corticotropin releasing factor antagonists | PFIZER INC. (US) | 2006-06-27 | — | — | US | disclosed |