Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433769 | 0.86 | CRHR1 (0.55) | CRHR1 | |
| SCHEMBL6430475 | 0.80 | CRHR1 (0.45) | CRHR1 | |
| SCHEMBL5843858 | 0.75 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL5844563 | 0.73 | CRHR1 (0.73) | CRHR1 | |
| Hydrochloric Acid SCHEMBL5844382 | 0.72 | CRHR1 (0.72) | CRHR1 | |
| Hydrochloric Acid SCHEMBL5844378 | 0.71 | CRHR1 (0.70) | CRHR1 | |
| SCHEMBL6429241 | 0.70 | CRHR1 (0.47) | CRHR1 | |
| SCHEMBL16606725 | 0.68 | CRHR1 (0.60) | CRHR1 | |
| SCHEMBL5844138 | 0.68 | CRHR1 (0.60) | CRHR1 | |
| SCHEMBL5843106 | 0.67 | CRHR1 (0.52) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6844351-B1 | Corticotropin releasing factor antagonists | PFIZER INC. (US) | 2005-01-18 | — | — | US | disclosed |