Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3931226 | 0.87 | NAMPT (0.48) | F2RL1NAMPTLMNAALDH1A1MEN1 | |
| Iodide SCHEMBL20475497 | 0.86 | NAMPT (0.47) | F2RL1NAMPTLMNAALDH1A1MEN1 | |
| SCHEMBL1259772 | 0.82 | TDP1 (0.56) | F2RL1LMNAALDH1A1ALOX5NPC1 | |
| SCHEMBL6573723 | 0.81 | FFAR1 (0.52) | LMNASMN1; SMN2NPC1RAB9AFFAR1 | |
| SCHEMBL6641533 | 0.81 | TSHR (0.48) | LMNAALDH1A1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL27581983 | 0.80 | MMP12 (0.61) | F2RL1LMNAALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL755111 | 0.79 | F2RL1 (0.57) | F2RL1ALOX5OR51E2CYP4F2CYP4A11 | |
| SCHEMBL28813051 | 0.79 | F2RL1 (0.57) | F2RL1ALDH1A1ALOX5OR51E2CYP4F2 | |
| SCHEMBL7178176 | 0.78 | IAPP (0.53) | F2RL1NAMPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL6646146 | 0.78 | HPGD (0.49) | ALDH1A1ALOX5MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074784-B2 | Nitrogen compounds such as methyl 4-(2-chloro-4-fluorophenyl) -2-(3,5-difluoropyridin-2-yl)-6-(4-morpholinylmethyl)-1,4-dihydropyrimidine -5-carboxylate, with mixtures of lamivudine and interferons, used as viricides; hepatitis | Goldmann, Siegfried (DE) | 2006-07-11 | — | — | US | disclosed |
| EP-1265889-B1 | MEDICAMENTS AGAINST VIRAL DISEASES | BAYER HEALTHCARE AG (DE) | 2004-06-16 | — | — | EP | disclosed |
| US-20030232842-A1 | Medicaments against viral diseases | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2003-12-18 | — | — | US | disclosed |
| EP-1265889-A1 | MEDICAMENTS AGAINST VIRAL DISEASES | Bayer Aktiengesellschaft (DE) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001068640-A1 | MEDICAMENTS AGAINST VIRAL DISEASES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232842-A1 | Medicaments against viral diseases | HAVCR2, ENTPD5, TYMP | F2RL1 3658/4885NAMPT 145/4885LMNA 3787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.