SCHEMBL584516

SCHEMBL584516

CC(C)C(CCc1ccccc1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.54
SMN1; SMN2 Q16637 3/20 0.51
KMT2A Q03164 3/20 0.51
MEN1 O00255 2/20 0.51
HTT P42858 1/20 0.51
HPGD P15428 1/20 0.51
ACE P12821 1/20 0.49
ALDH1A1 P00352 2/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
CNR2 P34972 1/20 0.46
SLC1A3 P43003 1/20 0.46
SLC1A2 P43004 1/20 0.46
SLC1A1 P43005 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3252245 0.89 GRIK1 (0.51) TSHRSMN1; SMN2KMT2AMEN1HTT
SCHEMBL5010036 0.86 TSHR (0.43) TSHRSMN1; SMN2KMT2AMEN1HTT
SCHEMBL7319532 0.86 MAPT (0.51) KMT2AHPGDALDH1A1
SCHEMBL3392225 0.85 TSHR (0.51) TSHRSMN1; SMN2KMT2AMEN1HTT
SCHEMBL27453354 0.85 SLC1A3 (0.51) TSHRSMN1; SMN2KMT2AMEN1HTT
SCHEMBL30136419 0.83 TDP1 (0.45) TSHRSMN1; SMN2KMT2AHPGDALDH1A1
SCHEMBL7698714 0.82 TSHR (0.45) TSHRSMN1; SMN2KMT2AMEN1HTT
SCHEMBL7698716 0.82 TSHR (0.45) TSHRSMN1; SMN2KMT2AMEN1HTT
SCHEMBL20363269 0.82 TSHR (0.49) TSHRSMN1; SMN2KMT2AMEN1HTT
SCHEMBL7698712 0.82 TSHR (0.45) TSHRSMN1; SMN2KMT2AMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4444108-B1 ALDEHYDE MIXTURES FOR FLAVOUR IMPROVEMENT SYMRISE AG (DE) 2025-09-10 EP claimed
EP-4161293-B1 FLAVOURING COMPOSITION WITH BALANCED TASTE PROFILE SYMRISE AG (DE) 2024-01-31 EP claimed
CN-117396591-A Fragrance and evaluation method for improving happy state 奇华顿股份有限公司 2024-01-12 CN claimed
EP-4161291-B1 FLAVORING COMPOSITIONS FOR TASTE IMPROVEMENT SYMRISE AG (DE) 2023-11-01 EP claimed
US-10876081-B2 Method for the production of scent capsules with improved surfactant stability SYMRISE AG (DE) 2020-12-29 US claimed
EP-3423028-B1 METHOD FOR THE PRODUCTION OF ENCAPSULATED FRAGRANCE WITH IMPROVED STABILITY AGAINST DETERGENTS SYMRISE AG (DE) 2020-04-08 EP claimed
EP-3006547-B1 FRAGRANCE-CONTAINING CAPSULE AND COSMETIC IN WHICH SAID CAPSULES ARE BLENDED SHISEIDO CO LTD (JP) 2019-10-30 EP claimed
EP-2742983-B1 Method for isolating fragrance and flavour compounds SYMRISE AG (DE) 2017-08-23 EP claimed
EP-2849718-B1 MIXTURES HAVING IMPROVED COOLING EFFECT SYMRISE AG (DE) 2017-02-01 EP claimed
US-9005688-B2 Thermally stable high impact flavoring particles SYMRISE AG (DE) 2015-04-14 US claimed
EP-2849718-A2 MIXTURES HAVING IMPROVED COOLING EFFECT Symrise AG (DE) 2015-03-25 EP claimed
WO-2013171018-A2 MIXTURES HAVING IMPROVED COOLING EFFECT SYMRISE AG (DE) 2013-11-21 WO claimed
US-20120107477-A1 THERMALLY STABLE HIGH IMPACT FLAVORING PARTICLES SYMRISE AG (DE) 2012-05-03 US claimed
EP-1716159-B1 BICYCLIC SILOXANE COMPOSITIONS FOR THE RELEASE OF ACTIVE INGREDIENTS MOMENTIVE PERFORMANCE MAT INC (US) 2011-07-13 EP claimed
EP-1697386-B1 ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES GEN ELECTRIC (US) 2007-10-10 EP claimed
EP-3663366-B1 USE OF PHYSIOLOGICAL COOLING INGREDIENTS AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS SYMRISE AG (DE) 2025-01-08 EP disclosed
CN-113950465-B Sandalwood type spice compound 西姆莱斯股份公司 2024-09-20 CN disclosed
WO-2002041861-A1 RHINOLOGICAL AGENTS HAARMANN & REIMER GMBH (DE) 2002-05-30 WO disclosed
WO-2001043567-A1 AROMAS AND AROMA COMPOSITIONS CONTAINING 4,8-DIMETHYL-3,7-NONADIEN-2-ONE, AND A METHOD FOR THE PRODUCTION THEREOF HAARMANN & REIMER GMBH (DE) 2001-06-21 WO disclosed
EP-1050574-A2 Mint and/or fruit flavour compositions HAARMANN & REIMER GMBH (DE) 2000-11-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10876081-B2 Method for the production of scent capsules with improved surfactant stability SMOX, LIPA, SGMS2 TSHR 4699/4885SMN1; SMN2 1541/4885KMT2A 1413/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.