Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8473200 | 0.88 | NR4A1 (0.57) | EGFRMAOBRAB9ASMN1; SMN2MAPT | |
| SCHEMBL18286487 | 0.84 | MMP1 (0.64) | SMN1; SMN2MAPTALDH1A1PLA2G4BL3MBTL1 | |
| SCHEMBL4152328 | 0.83 | EGFR (0.72) | EGFRHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL28292838 | 0.83 | NPC1 (0.66) | RAB9AMAPTALDH1A1PARP10PLA2G4B | |
| SCHEMBL2348514 | 0.82 | ALOX5 (0.60) | HDAC3HDAC1HDAC2NCOR2MAOB | |
| SCHEMBL6602564 | 0.81 | CES1 (0.58) | HDAC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL8008103 | 0.81 | FFAR1 (0.67) | MAOBL3MBTL1 | |
| SCHEMBL11135332 | 0.81 | MMP1 (0.59) | SMN1; SMN2MAPTALDH1A1PLA2G4BL3MBTL1 | |
| SCHEMBL12987281 | 0.80 | MAOB (0.71) | EGFRHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL9261139 | 0.80 | FFAR1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2636670-B1 | Process for preparing benzofurans | CAMBREX KARLSKOGA AB (SE) | 2016-06-01 | — | — | EP | disclosed |
| EP-2417099-B1 | NEW PROCESS FOR PREPARING HYDROXYLAMINES AND MEDICAMENTS | CAMBREX KARLSKOGA AB (SE) | 2015-12-23 | — | — | EP | disclosed |
| EP-2388256-B1 | Process for preparing benzofurans | CAMBREX KARLSKOGA AB (SE) | 2015-11-25 | — | — | EP | disclosed |
| US-20140206761-A1 | PROCESS FOR PREPARING HYDROXYLAMINES AND MEDICAMENTS | CAMBREX KARLSKOGA AB (SE) | 2014-07-24 | — | — | US | disclosed |
| US-8779201-B2 | Process for preparing benzofurans | CAMBREX KARLSKOGA AB (SE) | 2014-07-15 | — | — | US | disclosed |
| US-20130338398-A1 | Process for Preparing Benzofurans | CAMBREX KARLSKOGA AB (SE) | 2013-12-19 | — | — | US | disclosed |
| EP-2636670-A1 | Process for preparing benzofurans | Cambrex Karlskoga AB (SE) | 2013-09-11 | — | — | EP | disclosed |
| US-8519165-B2 | Process for preparing benzofurans | CAMBREX KARLSKOGA AB (SE) | 2013-08-27 | — | — | US | disclosed |
| EP-2200993-B1 | PROCESS FOR PREPARING BENZOFURANS | CAMBREX KARLSKOGA AB (SE) | 2012-08-29 | — | — | EP | disclosed |
| US-20120122971-A1 | NEW PROCESS FOR PREPARING HYDROXYLAMINES AND MEDICAMENTS | CAMBREX KARLSKOGA AB (SE) | 2012-05-17 | — | — | US | disclosed |
| EP-2417099-A1 | NEW PROCESS FOR PREPARING HYDROXYLAMINES AND MEDICAMENTS | Cambrex Karlskoga AB (SE) | 2012-02-15 | — | — | EP | disclosed |
| EP-2388256-A1 | Process for preparing benzofurans | Cambrex Karlskoga AB (SE) | 2011-11-23 | — | — | EP | disclosed |
| US-20100292319-A1 | PROCESS FOR PREPARING BENZOFURANS | CAMBREX KARLSKOGA AB (SE) | 2010-11-18 | — | — | US | disclosed |
| WO-2010116140-A1 | NEW PROCESS FOR PREPARING HYDROXYLAMINES AND MEDICAMENTS | CAMBREX KARLSKOGA AB (SE) | 2010-10-14 | — | — | WO | disclosed |
| EP-2200993-A2 | PROCESS FOR PREPARING BENZOFURANS | Cambrex Karlskoga AB (SE) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009044143-A2 | PROCESS FOR PREPARING BENZOFURANS | CAMBREX KARLSKOGA AB (SE) | 2009-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130338398-A1 | Process for Preparing Benzofurans | CYP2F1, CYP4X1, CYP3A4 | EGFR 4343/4885HDAC3 2352/4885HDAC1 2793/4885 |
| US-20140206761-A1 | PROCESS FOR PREPARING HYDROXYLAMINES AND MEDICAMENTS | CYP3A4, CYP1A2, CYP2D6 | EGFR 4471/4885HDAC3 2732/4885HDAC1 3266/4885 |
| US-20120122971-A1 | NEW PROCESS FOR PREPARING HYDROXYLAMINES AND MEDICAMENTS | CYP3A4, CYP1A2, CYP4B1 | EGFR 4435/4885HDAC3 2534/4885HDAC1 3154/4885 |
| US-20100292319-A1 | PROCESS FOR PREPARING BENZOFURANS | CYP2F1, CYP3A4, CYP4F3 | EGFR 4387/4885HDAC3 2124/4885HDAC1 3046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.