SCHEMBL5845285

SCHEMBL5845285

CCCCCOc1ccc2cc(S(=O)(=O)C(=[N+]=[N-])S(=O)(=O)c3cc4ccc(OCCCCC)cc4cc3OCCCCC)c(OCCCCC)cc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 2/20 0.41
THRB P10828 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
MTNR1A P48039 2/20 0.38
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA3 P07451 1/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
CA14 Q9ULX7 1/20 0.37
CA5B Q9Y2D0 1/20 0.37
NR5A1 Q13285 1/20 0.37
TP53 P04637 1/20 0.36
TSHR P16473 1/20 0.36
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5843770 0.99 THRA (0.42) THRATHRBNPC1RAB9AMTNR1A
SCHEMBL5842540 0.99 THRA (0.42) THRATHRBNPC1RAB9AMTNR1A
SCHEMBL5843220 0.99 THRA (0.42) THRATHRBNPC1RAB9AMTNR1A
SCHEMBL5845446 0.99 THRA (0.42) THRATHRBNPC1RAB9AMTNR1A
SCHEMBL5845486 0.99 THRA (0.42) THRATHRBNPC1RAB9AMTNR1A
SCHEMBL5845423 0.98 CA12 (0.39) THRATHRBNPC1RAB9AMTNR1A
SCHEMBL5845082 0.93 KAT6A (0.39) THRAMTNR1A
SCHEMBL5845171 0.91 MEN1 (0.38) THRATHRBMTNR1A
SCHEMBL5843877 0.88 PDIA6 (0.42) THRATHRBNPC1RAB9ACA12
SCHEMBL5845481 0.88 THRA (0.43) THRATHRBNPC1RAB9ANR5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7101651-B2 Sulfonyldiazomethanes, photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO.,LTD. (JP) 2006-09-05 US disclosed
US-20040166432-A1 Novel sulfonyldiazomethanes, photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040166432-A1 Novel sulfonyldiazomethanes, photoacid generators, resist compositions, and patterning process VEGFA, POLL, PIM3 THRA 1957/4885THRB 3044/4885NPC1 4879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.