Pyridoxal

Pyridoxal

SCHEMBL584646

Cc1ncc(CO)c(C=O)c1O.Cc1ncc(CO)c(C=O)c1O.O=P(O)(O)OP(=O)(O)O

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.78
ALDH1A1 P00352 8/20 0.78
LMNA P02545 6/20 0.78
HPGD P15428 5/20 0.78
MEN1 O00255 3/20 0.78
KMT2A Q03164 3/20 0.78
AOX1 Q06278 1/20 0.78
TRIM24 O15164 1/20 0.76
TRIM33 Q9UPN9 1/20 0.76
ESR1 P03372 1/20 0.69
PTGS1 P23219 1/20 0.69
ACP1 P24666 1/20 0.69
PDE4A P27815 1/20 0.69
P2RX1 P51575 1/20 0.69
P2RX2 Q9UBL9 1/20 0.69
PDXK O00764 1/20 0.56
HTT P42858 6/20 0.46
L3MBTL1 Q9Y468 4/20 0.46
SMN1; SMN2 Q16637 4/20 0.46
MAPT P10636 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridoxal SCHEMBL2223414 1.00 KDM4E (0.78) KDM4EALDH1A1LMNAHPGDMEN1
Triphosphate SCHEMBL28454699 0.95 KDM4E (0.74) KDM4EALDH1A1LMNAHPGDMEN1
Pyridoxal SCHEMBL5051304 0.93 KDM4E (0.72) KDM4EALDH1A1LMNAHPGDMEN1
Pyridoxal SCHEMBL27627958 0.91 KDM4E (0.88) KDM4EALDH1A1LMNAHPGDMEN1
Pyridoxal SCHEMBL5498057 0.91 KDM4E (0.88) KDM4EALDH1A1LMNAHPGDMEN1
Pyridoxal SCHEMBL30616198 0.91 KDM4E (0.88) KDM4EALDH1A1LMNAHPGDMEN1
Pyridoxal SCHEMBL28454700 0.91 KDM4E (0.88) KDM4EALDH1A1LMNAHPGDMEN1
Pyridoxal SCHEMBL9559097 0.91 KDM4E (0.88) KDM4EALDH1A1LMNAHPGDMEN1
Pyridoxal SCHEMBL27131 0.91 KDM4E (0.88) KDM4EALDH1A1LMNAHPGDMEN1
Pyridoxal SCHEMBL5051301 0.91 KDM4E (0.88) KDM4EALDH1A1LMNAHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021126989-A1 TWO-WAY MAGNETIC RESONANCE TUNING NANOPROBE ENHANCED SUBTRACTION IMAGING THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-06-24 WO claimed
EP-2547369-B1 A NANOPARTICLE COMPRISING A MICELLE FORMED BY AN AMPHIPHILIC BLOCK-COPOLYMER AND ENCAPSULATING A GADOLINIUM COMPLEX UNIV KING SAUD (SA) 2017-04-19 EP claimed
EP-2214718-B1 LOADABLE POLYMERIC PARTICLES FOR ENHANCED IMAGING IN CLINICAL APPLICATIONS AND METHODS OF PREPARING AND USING THE SAME BOSTON SCIENT LTD (BM) 2017-04-12 EP claimed
EP-2547369-A1 A NANOPARTICLE COMPRISING A MICELLE FORMED BY AN AMPHIPHILIC BLOCK- COPOLYMER AND ENCAPSULATING A GADOLINIUM COMPLEX King Saud University (SA) 2013-01-23 EP claimed
WO-2011113616-A9 A NANOPARTICLE COMPRISING A MICELLE FORMED BY AN AMPHIPHILIC BLOCK- COPOLYMER AND ENCAPSULATING A GADOLINIUM COMPLEX KING SAUD UNIVERSITY (SA) 2011-11-17 WO claimed
WO-2011113616-A1 A NANOPARTICLE COMPRISING A MICELLE FORMED BY AN AMPHIPHILIC BLOCK- COPOLYMER AND ENCAPSULATING A GADOLINIUM COMPLEX KING SAUD UNIVERSITY (SA) 2011-09-22 WO claimed
EP-2214718-A1 LOADABLE POLYMERIC PARTICLES FOR ENHANCED IMAGING IN CLINICAL APPLICATIONS AND METHODS OF PREPARING AND USING THE SAME CeloNova Biosciences, Inc. (US) 2010-08-11 EP claimed
WO-2009067105-A1 LOADABLE POLYMERIC PARTICLES FOR ENHANCED IMAGING IN CLINICAL APPLICATIONS AND METHODS OF PREPARING AND USING THE SAME CELONOVA BIOSCIENCES, INC. (US) 2009-05-28 WO claimed
EP-3998336-B1 MICROORGANISMS AND METHODS FOR PRODUCING CANNABINOIDS AND CANNABINOID DERIVATIVES UNIV CALIFORNIA (US) 2026-01-07 EP disclosed
US-12460185-B2 Optimized cannabinoid synthase polypeptides DEMETRIX, INC. (US) 2025-11-04 US disclosed
US-12215327-B2 Microorganisms and methods for producing cannabinoids and cannabinoid derivatives THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-02-04 US disclosed
US-12048710-B2 Compositions and methods for modification of biomolecules THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-07-30 US disclosed
US-20230340506-A1 Microorganisms and methods for producing cannabinoids and cannabinoid derivatives THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-10-26 US disclosed
US-11542512-B2 Microorganisms and methods for producing cannabinoids and cannabinoid derivatives THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-01-03 US disclosed
WO-2004064869-A2 AMYLOID-BINDING, METAL-CHELATING AGENTS THE GENERAL HOSPITAL CORPORATION (US) 2004-08-05 WO disclosed
US-6432918-B1 SYNTHETIC BLOOD; SUPPLYING OXYGEN THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2002-08-13 US disclosed
CN-1300824-A Polypeptide-serine/threonine dehybase 37 and polynucleotide for coding this polypeptide UNIV FUDAN (CN) 2001-06-27 CN disclosed
EP-0598837-A4 AMINO ACID, ESTER AND/OR CATECHOL CONTRAST AGENTS FOR MRI. UNIV CALIFORNIA (US) 1994-07-13 EP disclosed
EP-0598837-A1 AMINO ACID, ESTER AND/OR CATECHOL CONTRAST AGENTS FOR MRI THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1994-06-01 EP disclosed
WO-1993003351-A1 AMINO ACID, ESTER AND/OR CATECHOL CONTRAST AGENTS FOR MRI THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1993-02-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12048710-B2 Compositions and methods for modification of biomolecules PTMS, QPCT, ANPEP KDM4E 3669/4885ALDH1A1 3718/4885LMNA 1871/4885
US-11542512-B2 Microorganisms and methods for producing cannabinoids and cannabinoid derivatives CNR2, CNR1, FAAH KDM4E 913/4885ALDH1A1 2306/4885LMNA 4339/4885
US-12215327-B2 Microorganisms and methods for producing cannabinoids and cannabinoid derivatives CNR2, CNR1, FAAH KDM4E 913/4885ALDH1A1 2306/4885LMNA 4339/4885
US-20230340506-A1 Microorganisms and methods for producing cannabinoids and cannabinoid derivatives CNR2, CNR1, FAAH KDM4E 913/4885ALDH1A1 2306/4885LMNA 4339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.