Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | LIG1 | P18858 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24820969 | 0.84 | MT-CO2 (0.43) | ALOX15TSHRALDH1A1 | |
| SCHEMBL11473867 | 0.84 | MT-CO2 (0.43) | ALOX15TSHRALDH1A1 | |
| SCHEMBL24806685 | 0.84 | MT-CO2 (0.43) | ALOX15TSHRALDH1A1 | |
| SCHEMBL361341 | 0.76 | LMNA (0.43) | ALOX15TSHRKDM1ASLC6A2SLC6A4 | |
| SCHEMBL29088187 | 0.74 | MAPT (0.47) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL24806792 | 0.73 | KDM4E (0.43) | ALOX15TSHRKDM1AKDM4EALDH1A1 | |
| SCHEMBL19381902 | 0.73 | KDM1A (0.47) | KDM1ASLC6A2SLC6A4SLC6A3HRH3 | |
| SCHEMBL19381975 | 0.73 | KDM1A (0.47) | KDM1ASLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL16937013 | 0.72 | KDM1A (0.45) | KDM1ASLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL24807939 | 0.72 | CHRNB4 (0.42) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7126010-B2 | Benzylcycloalkyl amines as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2006-10-24 | — | — | US | disclosed |
| US-20050124671-A1 | Benzylcycloalkyl amines as modulators of chemokine receptor activity | WACKER DEAN A (US) | 2005-06-09 | — | — | US | disclosed |
| US-6864380-B2 | Benzylcycloalkyl amines as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2005-03-08 | — | — | US | disclosed |
| US-20040014758-A1 | Benzylcycloalkyl amines as modulators of chemokine receptor activity | WACKER DEAN A (US) | 2004-01-22 | — | — | US | disclosed |
| EP-1220836-A2 | BENZYLCYCLOALKYL AMINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Bristol-Myers Squibb Pharma Company (US) | 2002-07-10 | — | — | EP | disclosed |
| WO-2001028987-A1 | BENZYLCYCLOALKYL AMINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARMACEUTICALS COMPANY (US) | 2001-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014758-A1 | Benzylcycloalkyl amines as modulators of chemokine receptor activity | CCR3, CCR1, CCR10 | ALOX15 1689/4885TSHR 2607/4885KDM1A 2965/4885 |
| US-20050124671-A1 | Benzylcycloalkyl amines as modulators of chemokine receptor activity | CCR3, CCR1, CCR10 | ALOX15 1707/4885TSHR 2506/4885KDM1A 3597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.