Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10947300 | 0.76 | S100A4 (0.43) | MAPTALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL600297 | 0.76 | TTR (0.44) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL10945370 | 0.74 | — | — | |
| SCHEMBL5846673 | 0.72 | MAPT (0.68) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL10947560 | 0.69 | — | — | |
| SCHEMBL10948633 | 0.69 | — | — | |
| SCHEMBL70169 | 0.68 | CA12 (0.62) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL2268884 | 0.68 | MAPT (0.75) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL15855939 | 0.68 | MAPT (0.55) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL10949461 | 0.66 | CDC25B (0.36) | MAPTALDH1A1MAPK1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7088757-B1 | Use of spiro compounds as laser dyes | SEMICONDUCTORS GMBH (DE) | 2006-08-08 | — | — | US | disclosed |
| US-6861567-B2 | Spiro compounds, and their use | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2005-03-01 | — | — | US | disclosed |
| EP-0968507-B1 | PHOTOVOLTAIC CELL | COVION ORGANIC SEMICONDUCTORS (DE) | 2004-12-15 | — | — | EP | disclosed |
| US-6822094-B2 | AMORPHOUS SPIROBIFLUORENE COMPOUND USED IN A PHOTOVOLTIC CELL AS CHARGE TRANSPORTING MATERIAL | AVENTIS RESEARCH & TECHNOLOGIES, GMBH & CO. KG (DE) | 2004-11-23 | — | — | US | disclosed |
| EP-0935691-B1 | OPTICAL BRIGHTENING AGENT | COVION ORGANIC SEMICONDUCTORS (DE) | 2004-05-26 | — | — | EP | disclosed |
| US-6664071-B1 | Photoactive layer of a semiconductor having a band gap of greater than 2.5 eV; dye applied to the semiconductor; charge transport hole conductor layer; counterelectrode layer; insulating layers; one side is transparent | NANOGEN RECOGNOMICS GMBH (DE) | 2003-12-16 | — | — | US | disclosed |
| EP-0947006-B1 | RADIATION DETECTOR | COVION ORGANIC SEMICONDUCTORS (DE) | 2003-09-03 | — | — | EP | disclosed |
| US-20030111107-A1 | Spiro compounds and their use | MERCK OLED MATERIALS GMBH (DE) | 2003-06-19 | — | — | US | disclosed |
| US-20030065190-A1 | Spiro compounds, and their use | MERCK OLED MATERIALS GMBH (DE) | 2003-04-03 | — | — | US | disclosed |
| EP-0850492-B1 | PHOTO-VOLTAIC CELL WITH A SPIRO-COMPOUND | COVION ORGANIC SEMICONDUCTORS (DE) | 2003-03-12 | — | — | EP | disclosed |
| US-5885368-A | Photovoltaic cell | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-23 | — | — | US | disclosed |
| US-5840217-A | LIGHT-EMITTING, CHARGE-TRANSPORT, CHARGE-INJECTION MATERIALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-11-24 | — | — | US | disclosed |
| WO-1998048433-A1 | PHOTOVOLTAIC CELL | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) | 1998-10-29 | — | — | WO | disclosed |
| WO-1998042655-A1 | SPIRO COMPOUNDS AND THE USE THEREOF | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) | 1998-10-01 | — | — | WO | disclosed |
| EP-0850492-A1 | PHOTO-VOLTAIC CELL | Hoechst Research & Technology Deutschland GmbH & Co. KG (DE) | 1998-07-01 | — | — | EP | disclosed |
| WO-1998021764-A1 | RADIATION DETECTOR | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) | 1998-05-22 | — | — | WO | disclosed |
| WO-1998018996-A1 | OPTICAL BRIGHTENING AGENT | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) | 1998-05-07 | — | — | WO | disclosed |
| EP-0768563-A1 | Use of spiro compounds as active materials for non-linear optic | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-04-16 | — | — | EP | disclosed |
| WO-1997010617-A1 | PHOTO-VOLTAIC CELL | HOECHST RESEARCH & TECHNOLOGY DEUTSCHLAND GMBH & CO. KG (DE) | 1997-03-20 | — | — | WO | disclosed |
| EP-0676461-A2 | Spiro compounds and their application as electroluminescence materials | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030111107-A1 | Spiro compounds and their use | PKD1, PKD2, REN | MAPT 3788/4885CA12 3761/4885CA1 2830/4885 |
| US-20030065190-A1 | Spiro compounds, and their use | PKD1, REN, NR3C2 | MAPT 4218/4885CA12 1838/4885CA1 2296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.