Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 2/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5848153 | 0.99 | SIGMAR1 (0.57) | SIGMAR1HTR1APARP1HTR7 | |
| SCHEMBL5846215 | 0.86 | SIGMAR1 (0.63) | SIGMAR1HTR1APARP1HTR7 | |
| Hydrochloric Acid SCHEMBL5847569 | 0.85 | SIGMAR1 (0.62) | SIGMAR1HTR1APARP1HTR7 | |
| SCHEMBL256663 | 0.84 | SIGMAR1 (0.63) | SIGMAR1HTR1APARP1 | |
| SCHEMBL14601668 | 0.82 | SIGMAR1 (0.60) | SIGMAR1HTR1A | |
| SCHEMBL7297566 | 0.81 | SIGMAR1 (0.63) | SIGMAR1HTR1APARP1 | |
| SCHEMBL5544346 | 0.81 | SIGMAR1 (0.63) | SIGMAR1HTR1APARP1 | |
| SCHEMBL6160767 | 0.80 | SIGMAR1 (0.53) | SIGMAR1PARP1 | |
| Hydrochloric Acid SCHEMBL7299927 | 0.79 | SIGMAR1 (0.61) | SIGMAR1HTR1APARP1 | |
| SCHEMBL5846286 | 0.79 | SIGMAR1 (0.61) | SIGMAR1HTR1APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39113-E1 | Utilization of derivatives of tetrahydropyridines(or 4-hydroxypiperidines)-butylazols in the preparation of a medicament for the treatment of pain | LABORATORIES DEL DR. ESTEVE, S.A. (ES) | 2006-05-30 | — | — | US | claimed |
| EP-1097698-B1 | UTILIZATION OF DERIVATIVES OF TETRAHYDROPYRIDINES (OR 4-HYDROXYPIPERIDINES)-BUTYLAZOLS IN THE PREPARATION OF A MEDICAMENT FOR THE TREATMENT OF PAIN | ESTEVE LABOR DR (ES) | 2003-05-07 | — | — | EP | claimed |
| US-6384055-B1 | ANALGESICS | LABORATORIOS DEL DR. ESTEVES, S.A. (ES) | 2002-05-07 | — | — | US | claimed |
| EP-1097698-A2 | UTILIZATION OF DERIVATIVES OF TETRAHYDROPYRIDINES (OR 4-HYDROXYPIPERIDINES)-BUTYLAZOLS IN THE PREPARATION OF A MEDICAMENT FOR THE TREATMENT OF PAIN | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2001-05-09 | — | — | EP | claimed |