Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Butyltriphenylphosphonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 9/20 | 0.46 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyltriphenylphosphonium SCHEMBL30358591 | 0.98 | HIF1A (0.64) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL3418099 | 0.95 | HIF1A (0.61) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL159490 | 0.95 | HIF1A (0.61) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL584160 | 0.95 | HIF1A (0.61) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL8535782 | 0.95 | HIF1A (0.61) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL1063 | 0.95 | HIF1A (0.61) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL531998 | 0.93 | HIF1A (0.58) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Iodide SCHEMBL5088274 | 0.93 | HIF1A (0.58) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL7865507 | 0.93 | HIF1A (0.58) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL28007945 | 0.93 | HIF1A (0.58) | HIF1AALDH1A1CYP1A2CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 391 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957201-B | Preparation method of low-cyclic byproduct polybutylene succinate polyester | 万华化学集团股份有限公司 | 2023-10-20 | — | — | CN | claimed |
| CN-115872845-A | Preparation method of menthone | 万华化学集团股份有限公司 | 2023-03-31 | — | — | CN | claimed |
| CN-114957201-A | Preparation method of low-cyclic by-product poly (butylene succinate) polyester | 万华化学集团股份有限公司 | 2022-08-30 | — | — | CN | claimed |
| CN-110358069-B | Polyester with selenium-containing main chain and preparation method thereof | 浙江大学 | 2020-05-26 | — | — | CN | claimed |
| CN-110358069-A | A kind of main chain polyester containing selenium and preparation method thereof | 浙江大学 | 2019-10-22 | — | — | CN | claimed |
| CN-110204724-A | A method of preparing carbonyl sulfide co-production sulfur-containing polymer | 浙江大学 | 2019-09-06 | — | — | CN | claimed |
| CN-109180937-A | A method of preparing aliphatic poly thioether | 浙江大学 | 2019-01-11 | — | — | CN | claimed |
| CN-106543423-B | Fatty poly-ester carbonate composite material and preparation method | 河南大学 | 2018-12-28 | — | — | CN | claimed |
| CN-106543424-B | A kind of poly (propylene carbonate)/POSS hybrid material and preparation method thereof | 河南大学 | 2018-11-30 | — | — | CN | claimed |
| EP-2915848-B1 | THERMOSETTING RESIN COMPOSITION AND USE THEREOF | SHENGYI TECHNOLOGY CO LTD (CN) | 2018-05-30 | — | — | EP | claimed |
| CN-101553465-A | Method for producing tris(perfluoroalkanesulfonyl)methide acid salt | CENTRAL GLASS CO LTD (JP) | 2009-10-07 | — | — | CN | claimed |
| EP-2080753-A1 | METHOD FOR PRODUCING TRIS(PERFLUOROALKANESULFONYL)METHIDE ACID SALT | Central Glass Company, Limited (JP) | 2009-07-22 | — | — | EP | claimed |
| CN-100384909-C | Polycarbonate material in alternating structure | UNIV DALIAN SCIENCE & ENG (CN) | 2008-04-30 | — | — | CN | claimed |
| CN-1887934-A | Polycarbonate material in alternating structure | UNIV DALIAN SCIENCE & ENG (CN) | 2007-01-03 | — | — | CN | claimed |
| CN-1247566-C | Optical activity cyclic carbonates preparation method | UNIV DALIAN TECH (CN) | 2006-03-29 | — | — | CN | claimed |
| CN-1663978-A | Process for preparing polycarbonate with optical activity | UNIV DALIAN TECH (CN) | 2005-09-07 | — | — | CN | claimed |
| CN-1189246-C | High activity catalyzer utilized to synthesize cyclic carbonate | DALIAN UNIV OF SCIENCE AND TEC (CN) | 2005-02-16 | — | — | CN | claimed |
| CN-1560111-A | Preparation process of polyester carbonate with high molecular weight whole alternant structure | 大连理工大学 | 2005-01-05 | — | — | CN | claimed |
| CN-1544431-A | Optical activity cyclic carbonates preparation method | 大连理工大学 | 2004-11-10 | — | — | CN | claimed |
| CN-1415416-A | High activity catalyzer utilized to synthesize cyclic carbonate | DALIAN UNIV OF SCIENCE AND TEC (CN) | 2003-05-07 | — | — | CN | claimed |