Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Butyltriphenylphosphonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 8/20 | 0.42 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyltriphenylphosphonium SCHEMBL27564900 | 0.98 | HIF1A (0.58) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL2650050 | 0.98 | HIF1A (0.58) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL30358591 | 0.98 | HIF1A (0.64) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL27985987 | 0.96 | HIF1A (0.56) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL2650095 | 0.96 | HIF1A (0.56) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL584160 | 0.95 | HIF1A (0.61) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL584744 | 0.95 | HIF1A (0.61) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL8535782 | 0.95 | HIF1A (0.61) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL3418099 | 0.95 | HIF1A (0.61) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL159490 | 0.95 | HIF1A (0.61) | HIF1AALDH1A1CYP1A2CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3285 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4713317-A1 | A PROCESS FOR PURIFICATION OF ETHOFUMESATE | Adama Agan Ltd. (IL) | 2026-03-25 | — | — | EP | claimed |
| US-12358855-B2 | Catalytic cracking agent containing phosphorus-modified molecular sieve, preparation process thereof, preparation system and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2025-07-15 | — | — | US | claimed |
| WO-2025107369-A1 | APPARATUS SYSTEM AND METHOD FOR PREPARING CYCLIC CARBONATE BY CYCLOESTERIFICATION OF DIOL | 惠州市绿色能源与新材料研究院 | 2025-05-30 | — | — | WO | claimed |
| US-12296323-B2 | Phosphorus-modified MFI-structured molecular sieve, catalytic cracking auxiliary and catalytic cracking catalyst containing phosphorus-modified MFI-structured molecular sieve, and processes for preparing the same | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2025-05-13 | — | — | US | claimed |
| CN-119569369-A | Composite liquid cement grinding aid and preparation method thereof | 云南素原新材料有限公司 | 2025-03-07 | — | — | CN | claimed |
| US-20250066968-A1 | METHOD FOR DEGUMMING AND DECOLORIZING POLYESTER FABRIC | NAN YA PLASTICS CORPORATION (TW) | 2025-02-27 | — | — | US | claimed |
| CN-119507194-A | Method for removing glue and decoloring polyester fabric | 南亚塑胶工业股份有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-117563512-B | Device system and method for preparing cyclic carbonate through diol ring esterification | 惠州市绿色能源与新材料研究院 | 2024-12-03 | — | — | CN | claimed |
| CN-118994852-A | Flame-retardant epoxy resin composition, flame-retardant epoxy resin cured product, and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-11-22 | — | — | CN | claimed |
| WO-2024236570-A1 | A PROCESS FOR PURIFICATION OF ETHOFUMESATE | ADAMA AGAN LTD. (IL) | 2024-11-21 | — | — | WO | claimed |
| EP-0180471-B1 | NOVEL THERMOPLASTIC POLYESTER COMPOSITIONS CONTAINING CERTAIN LOW MOLECULAR WEIGHT DEPOXIDE RESINS AND HAVING IMPROVED IMPACT BEHAVIOUR | CELANESE CORPORATION (US) | 1992-03-04 | — | — | EP | claimed |
| US-5086114-A | Reacting anhydride-containing copolymer with diisocyanate and halogenated phthalic anhydride in the prense of quaternary phosphonium compound | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1992-02-04 | — | — | US | claimed |
| EP-0401589-A2 | Method of producing imide bond-containing resins | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1990-12-12 | — | — | EP | claimed |
| US-4658079-A | POLYMERIZED WITH SURFACE DEACTIVATED ZEOLITE CATALYST | MOBIL OIL CORPORATION (US) | 1987-04-14 | — | — | US | claimed |
| US-4537848-A | Positively charged toner compositions containing phosphonium charge enhancing additives | XEROX CORPORATION (US) | 1985-08-27 | — | — | US | claimed |
| US-4102912-A | Process to prepare polyhalodiphenyl carbonates | GENERAL ELECTRIC COMPANY (US) | 1978-07-25 | — | — | US | claimed |
| US-4101601-A | Epoxy-catalyst additive system to produce higher I.V. polybutylene terephthalate from low I.V. polymer | CELANESE CORPORATION (US) | 1978-07-18 | — | — | US | claimed |
| US-4066629-A | PROCESS FOR PREPARING CARBODIIMIDES UTILIZING A PHOSPHONIUM SALT CATALYST | CELANESE CORPORATION (US) | 1978-01-03 | — | — | US | claimed |
| US-3997705-A | Method of coagulating a fluoro-elastomer from an aqueous dispersion thereof | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) | 1976-12-14 | — | — | US | claimed |
| US-3939117-A | Process for producing a polyarylene ester | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-02-17 | — | — | US | claimed |