Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Butyltriphenylphosphonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 8/20 | 0.42 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyltriphenylphosphonium SCHEMBL30358591 | 0.98 | HIF1A (0.64) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL584744 | 0.95 | HIF1A (0.61) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL8535782 | 0.95 | HIF1A (0.61) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL159490 | 0.95 | HIF1A (0.61) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL584160 | 0.95 | HIF1A (0.61) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL1063 | 0.95 | HIF1A (0.61) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL7865507 | 0.93 | HIF1A (0.58) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL2650050 | 0.93 | HIF1A (0.58) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL28007945 | 0.93 | HIF1A (0.58) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Water SCHEMBL7695338 | 0.93 | HIF1A (0.58) | HIF1AALDH1A1CYP1A2CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116120519-A | Refining method of ultra-high purity epoxy resin | 惠柏新材料科技（上海）股份有限公司 | 2023-05-16 | — | — | CN | claimed |
| CN-108192075-A | Method for refining ultrahigh-purity epoxy resin | 惠柏新材料科技（上海）股份有限公司 | 2018-06-22 | — | — | CN | claimed |
| US-20130161840-A1 | STRIPPER SOLUTIONS EFFECTIVE FOR BACK-END-OF-LINE OPERATIONS | DYNALOY LLC (US) | 2013-06-27 | — | — | US | claimed |
| US-8440389-B2 | Stripper solutions effective for back-end-of-line operations | DYNALOY, LLC (US) | 2013-05-14 | — | — | US | claimed |
| US-20100221503-A1 | STRIPPER SOLUTIONS EFFECTIVE FOR BACK-END-OF-LINE OPERATIONS | DYNALOY LLC (US) | 2010-09-02 | — | — | US | claimed |
| WO-2010008877-A1 | STRIPPER SOLUTIONS EFFECTIVE FOR BACK-END-OF LINE OPERATIONS | DYNALOY LLC (US) | 2010-01-21 | — | — | WO | claimed |
| US-6316575-B1 | MELT TRANSESTERIFICATION OF DIOL COMPOUND AND CARBOANTE COMPOUND USING CATALYST COMPRISING A PHOSPHORUS-CONTAINING BASIC COMPOUND QUATERNARY PHOSPHONIUM SALT TO FORM POLYCARBONATE | IDEMITSU KOSAN CO., LTD. (JP) | 2001-11-13 | — | — | US | claimed |
| EP-0673959-B1 | Process for producing aromatic polycarbonate | MITSUBISHI CHEM CORP (JP) | 1998-10-28 | — | — | EP | claimed |
| US-5527875-A | Process for producing aromatic polycarbonate | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-06-18 | — | — | US | claimed |
| EP-0673959-A1 | Process for producing aromatic polycarbonate | Mitsubishi Chemical Corporation (JP) | 1995-09-27 | — | — | EP | claimed |
| US-12522632-B2 | Method for extracting keratin from wool/natural fibers using ionic liquids reinforced with sonication | Najran University (SA) | 2026-01-13 | — | — | US | disclosed |
| US-12460019-B2 | Preparation of regenerated polysaccharides | UNIVERSITAET ROSTOCK (DE) | 2025-11-04 | — | — | US | disclosed |
| CN-115175943-B | Preparation of regenerated polysaccharide | 罗斯托克大学 | 2024-12-17 | — | — | CN | disclosed |
| US-20240309240-A1 | POLISHING COMPOSITION, POLISHING METHOD, AND METHOD FOR PRODUCING SEMICONDUCTOR SUBSTRATE | FUJIMI INCORPORATED (JP) | 2024-09-19 | — | — | US | disclosed |
| US-20240239837-A1 | METHOD FOR EXTRACTING KERATIN FROM WOOL/NATURAL FIBERS USING IONIC LIQUIDS REINFORCED WITH SONICATION | Najran University (SA) | 2024-07-18 | — | — | US | disclosed |
| EP-0673959-A1 | Process for producing aromatic polycarbonate | Mitsubishi Chemical Corporation (JP) | 1995-09-27 | — | — | EP | disclosed |
| US-4395574-A | Phosphonium phenoxide catalysts for promoting reaction of epoxides with phenols and/or carboxylic acids | THE DOW CHEMICAL CO. (US) | 1983-07-26 | — | — | US | disclosed |
| EP-0019852-B1 | PHOSPHONIUM PHENOXIDE CATALYSTS, EPOXY RESIN CONTAINING SAME AND PROCESS FOR PROMOTING REACTION OF EPOXIDES WITH PHENOLS AND/OR CARBOXYLIC ACIDS | THE DOW CHEMICAL COMPANY (US) | 1983-07-20 | — | — | EP | disclosed |
| US-4302574-A | Phosphonium phenoxide catalysts for promoting reacting of epoxides with phenols and/or carboxylic acids | THE DOW CHEMICAL COMPANY (US) | 1981-11-24 | — | — | US | disclosed |
| EP-0019852-A1 | Phosphonium phenoxide catalysts, epoxy resin containing same and process for promoting reaction of epoxides with phenols and/or carboxylic acids | THE DOW CHEMICAL COMPANY (US) | 1980-12-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239837-A1 | METHOD FOR EXTRACTING KERATIN FROM WOOL/NATURAL FIBERS USING IONIC LIQUIDS REINFORCED WITH SONICATION | KRT18, CKAP4, ANKK1 | HIF1A 4183/4885ALDH1A1 4534/4885CYP1A2 4285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.