Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2679694 | 0.86 | DGAT1 (0.31) | DGAT1 | |
| SCHEMBL20299094 | 0.84 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL25287756 | 0.84 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL584369 | 0.78 | KLKB1 (0.35) | DGAT1 | |
| SCHEMBL27042148 | 0.71 | KLKB1 (0.31) | DGAT1 | |
| SCHEMBL27042261 | 0.71 | KLKB1 (0.33) | — | |
| SCHEMBL15564816 | 0.70 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL29260329 | 0.69 | DGAT1 (0.31) | DGAT1 | |
| SCHEMBL31501754 | 0.69 | ATR (0.34) | DGAT1 | |
| SCHEMBL17610630 | 0.68 | ALDH1A1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417138-A1 | PYRAZOLO [1, 5-A] PYRIMIDINE DERIVATIVES AS MTOR INHIBITORS | Schering Corporation (US) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010118207-A1 | PYRAZOLO [1, 5-A] PYRIMIDINE DERIVATIVES AS MTOR INHIBITORS | SCHERING CORPORATION (US) | 2010-10-14 | — | — | WO | disclosed |