Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.35 |
| ▸ | RHEB | Q15382 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14703718 | 0.76 | L3MBTL1 (0.38) | L3MBTL1TDP1NFE2L2HTR1ASLC6A2 | |
| SCHEMBL95848 | 0.76 | PARP10 (0.39) | L3MBTL1TDP1NFE2L2HTR1ASLC6A2 | |
| SCHEMBL6219566 | 0.76 | L3MBTL1 (0.38) | L3MBTL1TDP1NFE2L2HTR1ASLC6A2 | |
| SCHEMBL30773497 | 0.71 | HTR1A (0.55) | L3MBTL1TDP1HTR1ASLC6A2ALDH1A1 | |
| SCHEMBL2389927 | 0.71 | HTR1A (0.55) | L3MBTL1TDP1HTR1ASLC6A2ALDH1A1 | |
| SCHEMBL6289414 | 0.69 | HTR1A (0.59) | L3MBTL1TDP1HTR1ASLC6A2ALDH1A1 | |
| SCHEMBL6293091 | 0.69 | HTR1A (0.59) | L3MBTL1TDP1HTR1ASLC6A2ALDH1A1 | |
| SCHEMBL6289399 | 0.69 | HTR1A (0.59) | L3MBTL1TDP1HTR1ASLC6A2ALDH1A1 | |
| SCHEMBL28887844 | 0.69 | — | — | |
| SCHEMBL27715115 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7138538-B2 | Process for the separation of enantiomers and enantiopure reagent | SOLVAY (SOCIETE ANONYME) (BE) | 2006-11-21 | — | — | US | disclosed |
| US-6743373-B1 | REAGENT BASED ON ENANTIOPURE AMINO ACID IN WHICH AMINO GROUP CARRIES ACTIVATING GROUP TO FORM ACTIVE PRECURSOR OF ISOCYANATE GROUP AND CARBOXYL GROUP IS SUBSTITUTED; SEPARATION OF ENANTIOMERS HAVING FREE FUNCTIONAL GROUP | SOLVAY (SOCIETE ANONYME) (BE) | 2004-06-01 | — | — | US | disclosed |