Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5848006 | 0.90 | CA2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL5848467 | 0.87 | PTGS2 (0.60) | PTGS2PTGS1 | |
| SCHEMBL5847970 | 0.87 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL5848703 | 0.83 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL5850167 | 0.83 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL5850039 | 0.83 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL5850241 | 0.81 | PTGS2 (0.61) | PTGS2PTGS1 | |
| SCHEMBL5849698 | 0.81 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL5848498 | 0.81 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL5849700 | 0.80 | PTGS2 (0.65) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7112605-B2 | Sulfonyl-containing 3,4-diaryl-3-pyrrolin-2-ones, preparation method, and medical use thereof | Research Institute of Materia Medica Chinese Acadamy of Medical Sciences (CN) | 2006-09-26 | — | — | US | claimed |
| US-7112605-B2 | Sulfonyl-containing 3,4-diaryl-3-pyrrolin-2-ones, preparation method, and medical use thereof | Research Institute of Materia Medica Chinese Acadamy of Medical Sciences (CN) | 2006-09-26 | — | — | US | disclosed |