Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 18/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5849025 | 0.95 | P2RY12 (0.47) | P2RY12MEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL5849442 | 0.90 | P2RY12 (0.47) | P2RY12MEN1 | |
| SCHEMBL5848849 | 0.90 | HTR6 (0.48) | P2RY12MEN1 | |
| SCHEMBL5851053 | 0.90 | P2RY12 (0.47) | P2RY12MEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL5849233 | 0.90 | P2RY12 (0.47) | P2RY12MEN1 | |
| SCHEMBL5851499 | 0.89 | P2RY12 (0.48) | P2RY12MEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL5851544 | 0.89 | P2RY12 (0.46) | P2RY12MEN1 | |
| SCHEMBL5851437 | 0.88 | P2RY12 (0.52) | P2RY12MEN1 | |
| SCHEMBL5850931 | 0.88 | P2RY12 (0.46) | P2RY12MEN1 | |
| SCHEMBL5850808 | 0.88 | P2RY12 (0.46) | P2RY12MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7115741-B2 | 4-thieno[2,3-D]pyrimidin-4-YL piperazine compounds | ALEXION PHARMACEUTICALS, INC. | 2006-10-03 | — | — | US | disclosed |
| US-20030153556-A1 | Piperazine and homopiperazine compounds | MILLENNIUM PHARMACEUTICALS, INC. | 2003-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153556-A1 | Piperazine and homopiperazine compounds | HAMP, MPL, F2 | P2RY12 111/4885MEN1 2603/4885ALDH1A1 3346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.