Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5849986 | 0.84 | PTPN1 (0.46) | RAB9AMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11268098 | 0.81 | RAB9A (0.47) | RAB9AMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL4969955 | 0.81 | RAB9A (0.47) | RAB9AMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL5850108 | 0.77 | KDM4E (0.42) | RAB9AMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL4968860 | 0.70 | GAA (0.61) | RAB9AMAPTALDH1A1SMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL27699619 | 0.69 | KDM4E (0.46) | RAB9AMAPTALDH1A1SMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL5851393 | 0.69 | GAA (0.59) | MAPTALDH1A1SMN1; SMN2KDM4EGLA | |
| SCHEMBL5849893 | 0.68 | MAPT (0.78) | RAB9AMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8268318 | 0.67 | MAPT (0.44) | RAB9AMAPTALDH1A1SMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL5849632 | 0.67 | MAPT (0.76) | RAB9AMAPTALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6984646-B2 | Imidazopyridinones as p38 map kinase inhibitors | BAYER HEALHCARE AG (DE) | 2006-01-10 | — | — | US | disclosed |
| EP-1412353-B1 | IMIDAZOPYRIDINONES AS P38 MAP KINASE INHIBITORS | BAYER HEALTHCARE AG (DE) | 2005-03-02 | — | — | EP | disclosed |
| US-20040220208-A1 | Imidazopyridinones as p38 map kinase inhibitors | BAYER HEALTHCARE AG (DE) | 2004-11-04 | — | — | US | disclosed |
| EP-1412353-A1 | IMIDAZOPYRIDINONES AS P38 MAP KINASE INHIBITORS | Bayer HealthCare AG (DE) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003008413-A1 | IMIDAZOPYRIDINONES AS P38 MAP KINASE INHIBITORS | BAYER HEALTHCARE AG (DE) | 2003-01-30 | — | — | WO | disclosed |
| US-4720551-A | Chlorothienyl-imidazole propenones | SHIKOKU CHEMICALS CORPORATION (JP) | 1988-01-19 | — | — | US | disclosed |
| EP-0218398-A2 | Imidazole compound valuable as fungicidal agent and process for preparation thereof | SHIKOKU CHEMICALS CORPORATION (JP) | 1987-04-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220208-A1 | Imidazopyridinones as p38 map kinase inhibitors | MAPK1, MAPK3, MAP3K1 | RAB9A 1505/4885MAPT 1617/4885ALDH1A1 1216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.